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chlorhexidine gluconate (Dyna-Hex)

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Also Known As:

Dyna-Hex; Hibiclens; Peridex; 1,1'-HBCB; Chlorhexamed; Corsodyl ICI; Curasept ADS 220; Eludril; Gibitan; Hexidine; Hibident; Hibiscrub; Hibisol; Perio Chip; avagard; chlorhexidine bigluconate; chlorhexidine digluconate

Networked: 422 relevant articles (55 outcomes, 114 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 58
- Amidines: 11
  - Guanidines: 20
    - Biguanides: 294
      - Chlorhexidine: 1791
        chlorhexidine gluconate: 422

Experts

1.	Koji, Takehiko: 10 articles (05/2015 - 01/2003)
2.	Kohno, Shigeru: 10 articles (05/2015 - 01/2003)
3.	Nishino, Tomoya: 9 articles (05/2015 - 09/2003)
4.	Abe, Katsushige: 8 articles (04/2013 - 01/2003)
5.	Obata, Yoko: 7 articles (05/2015 - 04/2011)
6.	Miyazaki, Masanobu: 7 articles (04/2013 - 01/2003)
7.	Furusu, Akira: 6 articles (04/2013 - 09/2003)
8.	Weinstein, Robert A: 5 articles (04/2015 - 10/2007)
9.	Hayden, Mary K: 5 articles (04/2015 - 10/2007)
10.	Schwarz, Frank: 4 articles (11/2015 - 02/2005)

Related Diseases

1.	Infection 10/01/2006 - "A significant reduction or elimination of central line-associated bloodstream infections can occur with implementation of a comprehensive central line-associated bloodstream infection prevention program that includes staff education, hand hygiene, use of maximal sterile barrier precautions, chlorhexidine gluconate skin antisepsis, avoidance of femoral lines, empowerment of staff to stop the procedure if sterile technique is broken, and daily assessment of the continued need for a central line. " 10/01/1983 - "A preoperative hibiscrub shower did not affect the infection rate, even though it was responsible for a significant reduction in skin flora. " 09/01/2012 - "Previous work has shown that daily skin cleansing with chlorhexidine gluconate (CHG) is effective in preventing infection in the medical intensive care unit (MICU). " 05/01/2004 - "Although chlorhexidine gluconate has been used effectively to minimize surgical site infection in vaginal surgery, the possibility for adverse reaction should be considered." 09/01/1998 - "A 0.25% chlorhexidine gluconate gel was protective against chlamydial infection in all animals tested, had no adverse effect on the vaginal flora, and had minimal effect on cervicovaginal tissues after a single application."
2.	Gingivitis 11/01/1995 - "Peridex was the most effective in inhibiting plaque and gingivitis formation over that period of time. " 07/01/1990 - "In an examiner blind positive/negative controlled 6-month study, the efficacy of supragingival irrigation with 0.06% chlorhexidine gluconate on the marginal and subgingival microflora in naturally occurring gingivitis was evaluated. " 02/01/1990 - "The purpose of this study was to assess the efficacy of supragingival irrigation with 0.06% chlorhexidine gluconate (CHX) on naturally occurring gingivitis. " 07/01/2011 - "To compare the efficacy of turmeric mouthwash and chlorhexidine gluconate mouthwash in prevention of gingivitis and plaque formation. " 01/01/2015 - "Based on the observations of our study, it can be concluded that chlorhexidine gluconate as well as turmeric gel can be effectively used as an adjunct to mechanical plaque control in prevention of plaque and gingivitis. "
3.	Inflammation 03/01/2000 - "Chlorhexidine gluconate (0.12%), even in the absence of mechanical hygiene, was effective in inhibiting clinical signs of inflammation, associated with alterations in the subgingival microbial ecology, most notably Actinomyces spp." 07/01/2012 - "The aim of our clinical trial was to assess the efficacy of 0.1% turmeric mouthwash as an anti-plaque agent and its effect on gingival inflammation and to compare it with 0.2% chlorhexidine gluconate by evaluating the effect on plaque and gingival inflammation and on microbial load. " 03/01/1997 - "Several previous studies have evaluated the effects of 0.12% chlorhexidine digluconate (ChD) mouthrinses on plaque and gingival inflammation. " 12/01/1989 - "The purpose of this study was to determine the effect of a 0.125% chlorhexidine gluconate rinse on inflammation and bacterial plaque formation after periodontal surgery. " 06/01/2015 - "There was no difference in periodontal parameters after 7 days and 30 days of follow-up in Groups-1 and -2. EO-based oral rinses and chlorhexidine digluconate (CHX) are acceptable adjuncts to SRP in the treatment of periodontal inflammation."
4.	Peritoneal Fibrosis 01/01/2012 - "In this study, we investigated the role of lymphocytes in the development of peritoneal fibrosis induced by chlorhexidine gluconate (CG) by comparing the histological changes observed in severe combined immunodeficient (SCID) mice (largely lacking functional T and B lymphocytes) with those observed in wild-type (WT) mice. " 01/01/2012 - "To study this, we used microarray analysis and compared gene expression profiles of the peritoneum in control and chlorhexidine gluconate (CG)-induced peritoneal fibrosis mice. " 02/14/2009 - "The aim of the present study was to evaluate the effect of EPO on the development of experimental peritoneal fibrosis induced by chlorhexidine gluconate (CG). " 10/01/2007 - "The objective of the present study was to investigate the effect of matrix metalloproteinase inhibitor (ONO-4817), an anticancer agent with anti-angiogenesis and anti-infiltration effects, on the development of peritoneal fibrosis in chlorhexidine gluconate-induced PS rats. " 05/01/2015 - "Peritoneal fibrosis was induced by the injection of chlorhexidine gluconate (CG) into the peritoneal cavity of mice every other day for 3 weeks. "
5.	Dental Plaque 10/01/1981 - "The purpose of this study was to determine the effect of chlorhexidine digluconate mouthrinses on the development of dental plaque in man. " 07/01/2015 - "Effect of Cinnamon Extract and Chlorhexidine Gluconate (0.2%) on the Clinical Level of Dental Plaque and Gingival Health: A 4-Week, Triple-Blind Randomized Controlled Trial." 10/01/1981 - "The inhibitory effect of chlorhexidine digluconate on dental plaque formation. " 04/01/1977 - "Use of chlorhexidine gluconate to inhibit dental plaque accumulation in Macaca speciosa." 01/01/2009 - "It is concluded that Ozosept solution is effective in the control of dental plaque--biofilm accumulation and gingival inflammation, and produces no side effects related to chlorhexidine digluconate usage."

Related Drugs and Biologics

1.	Povidone-Iodine (Betadine)
2.	chlorhexidine gluconate (Dyna-Hex)
3.	Listerine
4.	Benzalkonium Compounds (Benzalkonium Chloride)
5.	Benzydamine (Tantum)
6.	Chlorhexidine
7.	Sodium Hypochlorite (Clorox)
8.	Calcium Hydroxide
9.	Iodine
10.	Small Interfering RNA (siRNA)

Related Therapies and Procedures

1.	Catheters
2.	Oral Hygiene (Dental Hygiene)
3.	Toothbrushing
4.	Home Care Dental Devices (Dental Floss)
5.	Debridement