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toloxatone

oxazolidinone derivative; psychotropic drug; structure

Also Known As:

(3-methyl)-3-phenyl-5-hydroxymethyl-2-oxazolidinone; 5-(hydroxymethyl)-3-(3-methylphenyl)-2- oxazolidinone

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - Oxazolidinones: 316
        toloxatone: 7

Related Diseases

1.	Poisoning 03/01/1990 - "[Acute toloxatone poisoning. " 03/01/1990 - "In 3 cases of severe poisoning, toloxatone was associated with tricyclic antidepressants. " 04/01/1997 - "Poisoning with new selective serotonin reuptake inhibitor antidepressants or monoamine-oxidase inhibitors type A (toloxatone, moclobemide) is usually not severe, but life-threatening serotonin syndromes may appear in case of drug combination with antidepressants. "
2.	Massive Hepatic Necrosis 01/01/1990 - "[Fatal fulminant hepatitis in 2 women taking toloxatone (Humoryl)]." 01/01/1990 - "We report two cases of fulminant hepatitis which might be due to toloxatone, a new type-A monoamine oxidase inhibitor. "
3.	Parkinsonian Disorders (Parkinsonism) 11/01/1986 - "[Toloxatone, parkinsonism and dopa therapy]."
4.	Serotonin Syndrome (Syndrome, Serotonin) 04/01/1997 - "Poisoning with new selective serotonin reuptake inhibitor antidepressants or monoamine-oxidase inhibitors type A (toloxatone, moclobemide) is usually not severe, but life-threatening serotonin syndromes may appear in case of drug combination with antidepressants. "
5.	Hepatitis 01/01/1990 - "Hepatitis occurred 20 days after the beginning of toloxatone administration in the first case and 138 days after the reintroduction of treatment in the second case. "

Related Drugs and Biologics

1.	Moclobemide (Arima)
2.	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)
3.	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)
4.	Fluvoxamine (Luvox)
5.	Tranylcypromine (Parnate)
6.	Monoamine Oxidase (MAO)
7.	Mianserin
8.	Maprotiline (Ludiomil)
9.	Imipramine (Janimine)
10.	Fluoxetine (Prozac)

Related Therapies and Procedures

1.	Therapeutics