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tolerin

endotoxin detoxified by irradiation

Networked: 8 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Biological Factors: 2472
- Biological Toxins: 20
  - Bacterial Toxins: 814
    - Endotoxins: 14335
      - tolerin: 8

Related Diseases

1.	Shock 09/01/1974 - "[The effect of endotoxin (Tolerin) detoxified by irradiation on the circulation in dogs with endotoxic shock]." 01/01/1978 - "The lethality of shock was greatly reduced by retreatment with radio-detoxified endotoxin (Tolerin). " 01/01/1981 - "It was found that the intraperitoneal administration of 4 mg of radiation-detoxified endotoxin (Tolerin) 48 hours prior to the inducement of shock prevents the drop in blood pressure and the decrease of cardiac output which promptly appear in the acute phase of endotoxin shock." 04/11/1999 - "Using ionizing radiation the author and co-workers produced a detoxified endotoxin preparation (Tolerin) which seems to be a suitable product for the increase of natural immunity (nonspecific resistance)-including activation of bone marrow in immunosuppressions, immunodeficiencies-protection against various types of shocks-radiation injury, septic/endotoxic shock, etc.- and increase of immunogen effect of antigens (e.g. "
2.	Radiation Injuries (Radiation Sickness) 04/11/1999 - "Using ionizing radiation the author and co-workers produced a detoxified endotoxin preparation (Tolerin) which seems to be a suitable product for the increase of natural immunity (nonspecific resistance)-including activation of bone marrow in immunosuppressions, immunodeficiencies-protection against various types of shocks-radiation injury, septic/endotoxic shock, etc.- and increase of immunogen effect of antigens (e.g. "
3.	Septic Shock (Toxic Shock Syndrome) 01/01/1993 - "Protective effect of radio-detoxified endotoxin (Tolerin) on the ultrastructure of pancreas in experimental endotoxin shock of rats." 01/01/1981 - "The protective action of the radiation detoxified endotoxin preparation (Tolerin) on the endotoxin shock of dogs was studied. " 01/01/1981 - "It was found that the intraperitoneal administration of 4 mg of radiation-detoxified endotoxin (Tolerin) 48 hours prior to the inducement of shock prevents the drop in blood pressure and the decrease of cardiac output which promptly appear in the acute phase of endotoxin shock."
4.	Body Weight (Weight, Body) 01/01/1994 - "One hundred microgram/100 g body weight (i.v.) of the radio-detoxified endotoxin preparation (RD-LPS, TOLERIN) prepared from Escherichia coli endotoxin by 60Co-gamma irradiation (150 KGy) increased the granulopectic activity of RES of intoxicated animals. " 01/01/1994 - "Both Escherichia coli endotoxin 100 micrograms/100 g i.v. (LPS) and radiodetoxified endotoxin 100 micrograms/100 g body weight i.v. (RD-LPS, TOLERIN) both increased the granulopectic activity of RES. The RD-LPS was more effective. "
5.	Myocardial Infarction 01/01/1981 - "[Protective effect on the liver through premedication with radiologically detoxicated endotoxin (Tolerin) in acute myocardial infarction in dogs]."

Related Drugs and Biologics

1.	Endotoxins
2.	Hepatitis B e Antigens
3.	Escherichia coli endotoxin

Related Therapies and Procedures

1.	Retreatment
2.	Premedication