grisorixin

ionophorous antibiotic of nigericin group isolated from cultures of a strain of Streptomyces griseus; RN given refers to parent cpd; structure in sixth source

Also Known As:

epigrisorixin; grisorixin, monocesium salt; grisorixin, monolithium salt; grisorixin, monopotassium salt; grisorixin, monorubidium salt; grisorixin, monosilver (+1) salt; grisorixin, monosodium salt; grisorixin, monothallium (+1) salt

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Boulahrouf, Abderrahmane: 1 article (01/2019)
2.	Defant, Andrea: 1 article (01/2019)
3.	Khenaka, Karima: 1 article (01/2019)
4.	Leulmi, Nassima: 1 article (01/2019)
5.	Mancini, Ines: 1 article (01/2019)
6.	Sighel, Denise: 1 article (01/2019)

Related Diseases

1.	Glioblastoma (Glioblastoma Multiforme) 01/01/2019 - "Nigericin and grisorixin methyl ester from the Algerian soil-living Streptomyces youssoufiensis SF10 strain: a computational study on their epimeric structures and evaluation of glioblastoma stem cells growth inhibition." 01/01/2019 - "Both nigericin sodium salt and grisorixin methyl ester showed to affect glioblastoma stem cells proliferation in a dose-dependent manner, with a higher activity for the more lipophilic grisorixin methyl ester (GI50 values of 3.85 and 3.05 μM for VIPI and COMI human glioblastoma stem cells, respectively)."
2.	Hypoxia (Hypoxemia) 05/01/1986 - "These beneficial effects were short-lasting and no deleterious effects were found on the ultrastructure of hearts subjected to grisorixin whether after hypoxia or after reoxygenation."

Related Drugs and Biologics

1.	Nigericin
2.	Esters
3.	Sodium
4.	Salts