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obelin

calcium-sensitive photoprotein obtained from the hydroid Obelia geniculata

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Luminescent Proteins: 39
    - obelin: 6

Experts

1.	Bashmakova, Eugenia E: 1 article (01/2022)
2.	Frank, Ludmila A: 1 article (01/2022)
3.	Kudryavtsev, Alexander N: 1 article (01/2022)
4.	Panamarev, Nikita S: 1 article (01/2022)
5.	Granovsky, I E: 1 article (12/2004)
6.	Ivashina, T V: 1 article (12/2004)
7.	Ksenzenko, V N: 1 article (12/2004)
8.	Shaloiko, L A: 1 article (12/2004)
9.	Shirokov, V A: 1 article (12/2004)
10.	Spirin, A S: 1 article (12/2004)

Related Diseases

1.	Polyps 12/20/2004 - "The 61 nt 5'-untranslated region (5'-UTR) of mRNA encoding for a light-emitting protein of hydroid polyp Obelia longissima, obelin, is shown to provide a high level of cap-independent translation of heterologous mRNAs in cell-free translation systems based on wheat germ extracts. " 05/15/1999 - "The marine polyp Obelia longissima produces a protein, obelin, which emits light in a calcium-dependent manner. " 02/14/1995 - "Sequence of the cDNA encoding the Ca(2+)-activated photoprotein obelin from the hydroid polyp Obelia longissima."
2.	Shock 01/01/1995 - "A constant luminescence of intact cells loaded with obelin following hypoosmotic shock was observed in three independent experiments." 01/01/1995 - "The maximum incorporation of obelin into these cells was achieved using the hypoosmotic shock technique. " 01/01/1995 - "An attempt was taken to incorporate Ca2(+)-dependent photoprotein obelin into young brown adipocytes using the three methods: 1) osmotic lysis of pinocytotic vesicles; 2) electroporation in a high electric field; 3) hypoosmotic shock. "
3.	Melanoma (Melanoma, Malignant) 01/01/2022 - "Two variants of Ca2+-regulated photoprotein obelin, extended from the N-terminus with small tumor markers - melanoma inhibitory activity protein (MIA) and survivin, one of the protein inhibitors of apoptosis, were designed, obtained and studied. "
4.	Hemolysis 10/15/1978 - "2% of original haemoglobin, 150mM-K+, 0.5MM-ATP, 10(3)--10(4) obelin luminescence counts/10(6) 'ghosts', which were relatively impermeable to Ca2+ and in which cyclic AMP formation was stimulated by beta-adrenergic agonists over a concentration range similar to that for intact cells, could be prepared after haemolysis in 6mM-NaCl3mM-MgCl2/50mM-Tes, pH7, and resealing for 30min at 37 degrees C in the presence of ATP and 150mM-KCl. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Luminescent Proteins
3.	Complementary DNA (cDNA)
4.	Magnesium Chloride
5.	Tumor Biomarkers (Tumor Markers)
6.	Messenger RNA (mRNA)
7.	Calcium
8.	Adrenergic beta-Agonists (beta-Adrenergic Agonists)
9.	Adenosine Triphosphate (ATP)
10.	Cyclic AMP (AMP, Cyclic)