viriditoxin

metabolite of Spicaria divaricata; structure

Also Known As:

3,3'-di-(methoxycarbonylmethyl)- 3,3',4,4'-tetrahydro-9,9',10,10'-tetrahydroxy-7,7'- dimethoxy-1,1'-dioxo-8,8'-bi-1H-naphtho(2,3-c)pyran; SC-28762; 3,3',4,4'-tetrahydro-9,9',10,10'-tetrahydroxy-7,7'-dimethoxy-1,1'-dioxo(8,8'-bi-1H-naphtho(2,3-c) pyran)-3,3'-diacetic acid, dimethyl ester

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Jung, Jee H: 2 articles (08/2020 - 12/2014)
2.	Cao, Jiafu: 1 article (08/2020)
3.	Ju, Zhiran: 1 article (08/2020)
4.	Jung, Young-Suk: 1 article (08/2020)
5.	Kim, Eun La: 1 article (08/2020)
6.	Li, Dandan: 1 article (08/2020)
7.	Su, Mingzhi: 1 article (08/2020)
8.	Zhao, Changhao: 1 article (08/2020)
9.	Kim, Hyung Sik: 1 article (12/2014)
10.	Kim, Tae Hyung: 1 article (12/2014)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 12/01/2014 - "The present study was designed to investigate the antitumor effects of viriditoxin (VDT) against human prostate cancer cells. " 12/01/2014 - "Viriditoxin regulates apoptosis and autophagy via mitotic catastrophe and microtubule formation in human prostate cancer cells."
2.	Neoplasms (Cancer) 08/27/2020 - "Given the close structural homology between FtsZ and tubulin, we investigated the potential antimitotic effects of viriditoxin on human cancer cells. "
3.	Lymphoma (Lymphomas) 11/08/2022 - "Here, we identify the mycotoxin viriditoxin (VDT), derived from the endophytic fungus Cladosporium cladosporioides, as an interesting candidate for leukemia and lymphoma treatment. " 11/08/2022 - "The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism."
4.	Leukemia 11/08/2022 - "Here, we identify the mycotoxin viriditoxin (VDT), derived from the endophytic fungus Cladosporium cladosporioides, as an interesting candidate for leukemia and lymphoma treatment. " 11/08/2022 - "The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism."
5.	Ischemia 11/01/1984 - "Finally, two hemorrhagic toxins (hemorrhagic toxin b and viriditoxin) are myotoxic; apparently, they secondarily to ischemia which develops in muscular tissue as a consequence of the hemorrhagic action of these toxins."

Related Drugs and Biologics

1.	Antimitotic Agents
2.	Tubulin
3.	Mycotoxins
4.	atrolysin B