palytoxin

11/01/1989 - "Structure-activity studies of the nonphorbol tumor promoter palytoxin in Swiss 3T3 cells."
03/01/2011 - "Although known for its acutely toxic action, palytoxin has also been identified as a type of carcinogenic agent called a tumor promoter. "
01/01/2007 - "Palytoxin is a novel skin tumor promoter, which has been used to help probe the role of different types of signaling mechanisms in carcinogenesis. "
01/01/2007 - "Palytoxin: exploiting a novel skin tumor promoter to explore signal transduction and carcinogenesis."
01/01/2006 - "Cell transforming activity of palytoxin, a non-TPA type tumor-promoter, was investigated with the two-stage transformation assay using Balb/c 3T3 cells. "

01/01/2013 - "In our present study, an LC-MS/MS method for palytoxin and its analogues in the blue humphead parrotfish samples causing the human poisoning cases in 2011 was developed and the samples were analysed by using the newly developed LC-MS/MS method. "
10/01/2015 - "Most incidents of palytoxin poisoning have manifested after oral intake of contaminated seafood. "
01/01/2015 - "A Case of Palytoxin Poisoning in a Home Aquarium Enthusiast and His Family."
12/01/2014 - "Palytoxin poisoning is rarely reported and is difficult to diagnose in the absence of laboratory confirmation. "
12/01/2014 - "We present an unusual outbreak of palytoxin poisoning associated with the consumption of Goldspot herring (Herklotsichthys quadrimaculatus). "

11/01/2007 - "Palytoxin, found in marine fish, has been associated with rhabdomyolysis, and may serve as a model for further study of the suspected toxin responsible for rhabdomyolysis after consumption of fresh water fish. "
03/01/1998 - "A 55-year-old man had rhabdomyolysis and myocardial damage induced by palytoxin. "
03/01/1998 - "Rhabdomyolysis and myocardial damage induced by palytoxin, a toxin of blue humphead parrotfish."

12/01/1988 - "Unlike the results of previous studies with another tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, palytoxin did not induce squamous differentiation of normal bronchial epithelial cells and was equally cytotoxic for normal human bronchial epithelial cells, a human lung tumor cell line, and human bronchial epithelial cells immortalized by infection with adenovirus 12-SV40 hybrid virus (BEAS-2B cells). "

01/01/2013 - "Extracts from the marine dinoflagellates Gambierdiscus, Ostreospis and mat-forming cyanobacteria as well as fish, giant clams and sea urchin samples were examined for the presence of CTXs and palytoxin (PLTX) by using the neuroblastoma cell-based assay (CBA-N2a). "
02/01/2009 - "With the aim of replacing current biological assays, such as the mouse or hemolytic assays, we investigated using the Neuro-2a neuroblastoma cell line to detect palytoxin and related compounds. "
09/01/2008 - "Then, in vitro cytotoxic effects of palytoxin were characterized on human neuroblastoma cells. "
09/01/2008 - "Characteristics of palytoxin-induced cytotoxicity in neuroblastoma cells."
01/01/1990 - "Palytoxin-induced whole-cell and single channel currents were recorded in mouse neuroblastoma cells. "