HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

4,4'-dihydroxystilbene

Also Known As:

4,4'-dihydroxy-trans-stilbene; 4,4'-stilbenediol

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        4,4'-dihydroxystilbene: 7

Experts

1.	Stivala, Lucia Anna: 4 articles (02/2016 - 07/2009)
2.	Bianchi, Livia: 3 articles (02/2016 - 10/2011)
3.	Maccario, Cristina: 3 articles (02/2016 - 10/2011)
4.	Savio, Monica: 3 articles (02/2016 - 10/2011)
5.	Forti, Luca: 3 articles (11/2012 - 07/2009)
6.	Ferraro, Daniela: 2 articles (02/2016 - 11/2012)
7.	Pizzala, Roberto: 2 articles (11/2012 - 10/2011)
8.	Cao, Yihai: 1 article (02/2016)
9.	Corana, Federica: 1 article (02/2016)
10.	Jensen, Lasse D: 1 article (02/2016)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 11/01/2012 - "The resveratrol analog 4,4'-dihydroxy-trans-stilbene suppresses transformation in normal mouse fibroblasts and inhibits proliferation and invasion of human breast cancer cells." 08/28/2006 - "Proteasome-independent down-regulation of estrogen receptor-alpha (ERalpha) in breast cancer cells treated with 4,4'-dihydroxy-trans-stilbene." 08/28/2006 - "In this study, we observed that treatment of cultured MCF-7 and T47D human breast cancer cells with the low affinity ER ligand, 4,4'-dihydroxy-trans-stilbene (4,4'-DHS), inhibited the transcriptional activity of ERalpha and induced slow and gradual decrease in the amount of ERalpha protein (henceforth referred to as down-regulation of ERalpha). " 07/01/2009 - "We assessed structure-activity relationships of RSV and the analogs 4,4'-dihydroxystilbene (4,4'-DHS), 3,5-dihydroxystilbene (3,5-DHS), 3,4'-dihydroxystilbene (3,4'-DHS), 4-hydroxystilbene (4-HS) using as model systems the ERalpha-positive and negative MCF7 and SkBr3 breast cancer cells, respectively. "
2.	Neoplasms (Cancer) 07/25/2022 - "Here we studied the activity of RSV and of its analogue 4,4'-dihydroxystilbene (DHS) in C57BL/6J mice bearing cancers resulting from Lung Lewis Carcinoma (LLC) cell implantation, considering tumour mass weight, angiogenesis, cell proliferation and death, autophagy, as well as characterization of their immune microenvironment, including infiltrating cancer-associated fibroblasts (CAFs). " 02/01/2016 - "We investigated the preventive effects of resveratrol analogue 4,4'-dihydroxy-trans-stilbene (DHS) on cancer invasion and metastasis. " 02/01/2016 - "Resveratrol analogue 4,4'-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis." 01/01/2016 - "Both 2,3- and 4,4'-dihydroxystilbene (at 10 and 25 mg/kg, twice daily) inhibited tumor growth and metastasis to the lung in mice. "
3.	Neoplasm Metastasis (Metastasis) 02/01/2016 - "We investigated the preventive effects of resveratrol analogue 4,4'-dihydroxy-trans-stilbene (DHS) on cancer invasion and metastasis. " 02/01/2016 - "Resveratrol analogue 4,4'-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis." 01/01/2016 - "Both 2,3- and 4,4'-dihydroxystilbene (at 10 and 25 mg/kg, twice daily) inhibited tumor growth and metastasis to the lung in mice. "
4.	Lewis Lung Carcinoma 07/25/2022 - "Resveratrol and Its Analogue 4,4'-Dihydroxy-trans-stilbene Inhibit Lewis Lung Carcinoma Growth In Vivo through Apoptosis, Autophagy and Modulation of the Tumour Microenvironment in a Murine Model."
5.	Cardiovascular Diseases (Cardiovascular Disease) 10/01/2011 - "On the basis of these results, the resveratrol analogue 4,4'-dihydroxy-trans-stilbene could be a promising chemopreventive agent against cardiovascular diseases."

Related Drugs and Biologics

1.	Estrogen Receptor alpha
2.	Proteins (Proteins, Gene)
3.	Ligands
4.	Resveratrol
5.	Proteasome Endopeptidase Complex (Proteasome)
6.	Dihydrotachysterol (AT 10)
7.	3,4'-dihydroxystilbene
8.	3,5-dihydroxystilbene
9.	4-hydroxystilbene