bredinin (mizoribine)

01/01/2013 - "We investigated the efficacy of a high-dose intermittent dosing treatment method (weekly mizoribine pulse therapy) conceived in the hope of achieving better efficacy by increasing the peak blood levels of mizoribine in patients with refractory lupus nephritis. "
01/01/2013 - "Intermittent administration of mizoribine can increase blood levels and may be effective for refractory lupus nephritis."
11/01/2013 - "Study of the efficacy of mizoribine in lupus nephritis in Chinese patients."
01/01/2013 - "Efficacy of weekly mizoribine pulse therapy in refractory lupus nephritis."
01/01/2008 - "A case of lupus nephritis improved after appropriately adjusting the dosage of mizoribine."

07/01/2002 - "A novel immunosuppressant, mizoribine (MZB), has recently been reported to be effective in the treatment of IgA nephropathy (IgAN), although its mechanism of action remains unknown. "
04/01/2008 - "Recent clinical trials have shown a beneficial effect of mizoribine (Miz), an immunosuppressive drug, in the treatment of new-onset pediatric IgA nephropathy (IgAN). "
11/01/2015 - "Single-course steroid pulse therapy combined with mizoribine was considered to have a protective effect on the renal function in IgA nephropathy, especially accompanying renal dysfunction."
05/01/2008 - "Combination therapy with mizoribine for severe childhood IgA nephropathy: a pilot study."
04/01/2008 - "Use of mizoribine as a rescue drug for steroid-resistant pediatric IgA nephropathy."

07/01/2012 - "To evaluate the efficacy of single-dose oral mizoribine (MZB) pulse therapy given twice weekly for frequently relapsing steroid-dependent nephrotic syndrome (FR-SDNS). "
03/01/2008 - "To evaluate the efficacy of oral mizoribine (MZB) pulse therapy given twice a week for frequently relapsing steroid-dependent nephrotic syndrome (FR-SDNS). "
01/01/2007 - "We assessed the efficacy of a single dose of oral mizoribine (MZB) pulse therapy two times per week for children with frequently relapsing nephrotic syndrome (FRNS). "
01/01/2007 - "Efficacy of single dose of oral mizoribine pulse therapy two times per week for frequently relapsing nephrotic syndrome."
07/01/2012 - "Effect of single-dose oral mizoribine pulse therapy twice per week for frequently relapsing steroid-dependent nephrotic syndrome."

11/01/2014 - "To evaluate the correlation between the efficacy of mizoribine (MZR) and the factors that might effect MZR concentration: renal function and dosage and administration of MZR in patients with rheumatoid arthritis (RA). "
11/01/2014 - "The efficacy of mizoribine for the treatment of rheumatoid arthritis and its correlation with renal function."
11/01/2012 - "The efficacy of mizoribine (MZR) in treatment of rheumatoid arthritis (RA) was retrospectively investigated in terms of drug survival, improvement in Disease Activity Score-28 (DAS28)-C-reactive protein (CRP), and blood MZR concentration obtained 3 h after dosing (MZR-C3). "
11/01/2012 - "An investigation of the correlation between blood concentration of mizoribine and its efficacy in treatment of rheumatoid arthritis based on indices of drug survival and improvement in DAS28-CRP."
04/01/2011 - "To determine the efficacy and safety of single-dose mizoribine (MZR) for patients with rheumatoid arthritis (RA), a 6-month, single-arm, open-label, prospective observation study was performed. "

04/01/2002 - "Our preliminary study demonstrated that mizoribine could reduce the amount of proteinuria in children with IgAN. "
12/01/2009 - "Mizoribine was started but proteinuria persisted. "
01/01/2012 - "Successful treatment of adult IgA nephropathy with nephrotic-level proteinuria by combination therapy including long-term coadministration of mizoribine."
11/01/2008 - "Mizoribine for relapsed proteinuria in an adult IgA nephropathy patient."
08/01/2013 - "The addition of prednisone after mizoribine monotherapy can be beneficial for all IMN patients with nephrotic-range proteinuria syndrome. "