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azelaic acid (Azelex)

Subscribe to New Research on azelaic acid

RN given refers to parent cpd; structure

Also Known As:

Azelex; Finacea; nonanedioic acid; azelaic acid, dilithium salt; azelaic acid, dipotassium salt; azelaic acid, disodium salt; azelaic acid, monosodium salt; azelaic acid, potassium salt; azelaic acid, sodium salt

Networked: 216 relevant articles (42 outcomes, 55 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 58
- Carboxylic Acids: 83
  - Acyclic Acids
    - Dicarboxylic Acids: 76
      - azelaic acid: 216

Experts

1.	Del Rosso, James Q: 12 articles (12/2014 - 01/2004)
2.	Draelos, Zoe Diana: 5 articles (07/2015 - 10/2004)
3.	Fleischer, Alan B: 5 articles (11/2010 - 11/2003)
4.	Elewski, Boni E: 4 articles (07/2015 - 11/2003)
5.	Graupe, Klaus: 4 articles (09/2010 - 06/2003)
6.	Thiboutot, Diane: 4 articles (01/2008 - 06/2003)
7.	van Zuuren, Esther J: 3 articles (12/2015 - 01/2011)
8.	Fedorowicz, Zbys: 3 articles (12/2015 - 01/2011)
9.	Staedtler, Gerald: 3 articles (07/2015 - 06/2010)
10.	Kircik, Leon H: 3 articles (12/2014 - 06/2011)

Related Diseases

1.	Rosacea (Acne Rosacea) 10/01/2008 - "Clinical studies have shown that azelaic acid 15% gel is an effective and safe first-line topical therapeutic option in patients with mild-to-moderate papulopustular rosacea. " 06/01/2008 - "Twice-daily azelaic acid (AzA) is the conventional regimen for papulopustular rosacea, but once-daily AzA may be equally effective, with greater convenience and dosing flexibility. " 02/01/2006 - "Azelaic acid (AzA) initially was released in a 20% cream formulation, which has been shown to be effective in the treatment of mild to moderate rosacea. " 01/01/2004 - "Azelaic acid is a naturally occurring, straight-chain dicarboxylic acid which is effective in the treatment of rosacea, presumably on account of its anti-inflammatory properties. " 05/01/2007 - "Azelaic acid 15% gel is considered effective and safe as a therapy for inflammatory papulo-pustular rosacea and is suitable for use on all skin types."
2.	Melanosis (Freckles) 10/01/2012 - "This study shows the efficacy of low-fluence QSNYL, topical 20% azelaic acid cream and their combination in melasma. " 10/01/2012 - "These patients were randomly divided in three groups (group A = 20 patients of melasma treated with low-fluence QSNYL at weekly intervals, group B = 20 patients of melasma treated with twice daily application of 20% azelaic acid cream and group C = 20 patients of melasma treated with combination of both). " 01/01/2002 - "Azelaic acid (AZA) 20% is considered efficacious in the treatment of melasma, although the response is rather slow. " 01/01/2002 - "A comparative study of 20% azelaic acid cream monotherapy versus a sequential therapy in the treatment of melasma in dark-skinned patients." 01/01/1989 - "[Use of a cream based on 20% azelaic acid in the treatment of melasma]."
3.	Acne Vulgaris 04/01/1989 - "Extensive multi-centre clinical trials have established that topical azelaic acid (a 20% cream) is an effective treatment for all types of acne. " 10/01/1989 - "Azelaic acid is effective in the treatment of acne because it possesses an activity against all of these factors. " 03/01/2007 - "Our objective in this study was to evaluate the efficacy of 20% azelaic acid gel in the treatment of mild to moderate acne vulgaris. " 03/01/2007 - "Efficacy of topical azelaic acid gel in the treatment of mild-moderate acne vulgaris." 01/01/1989 - "Preliminary clinical studies (2) proved the effectiveness of topical azelaic acid (AZA) in the treatment of acne vulgaris. "
4.	Erythema 05/01/2004 - "Azelaic acid 15% gel is a new first-tier topical agent proven effective in reducing inflammatory lesions and erythema. " 11/01/1999 - "Azelaic acid cream produced significantly greater mean reductions in total inflammatory lesions than did vehicle (azelaic acid: 73.4%; vehicle: 50.6%; (p = 0.011), and erythema severity score (azelaic acid: 47.9%; vehicle: 37.9%; (p = 0.031). " 01/01/2004 - "In all three studies, azelaic acid 15% gel recipients experienced continuous decreases in lesion counts and erythema throughout the 12- to 15-week treatment periods. " 01/01/2009 - "Azelaic acid cream was significantly more effective on inflammatory lesions but not erythema than the other two creams. " 06/01/1999 - "A reduction in erythema tended toward significance with azelaic acid at week 15. "
5.	Hutchinson's Melanotic Freckle (Lentigo Maligna) 11/01/1985 - "Azelaic acid was successfully used in the clinical treatment of 7 cases of lentigo maligna in that remission of the lesions was observed in all our patients. " 05/01/1993 - "Treatment of lentigo maligna with azelaic acid." 01/01/1989 - "The effect of azelaic acid is illustrated in a patient with lentigo maligna monitored clinically, histologically and ultrastructurally over the past 5 years." 01/01/1989 - "Topically applied azelaic acid led to complete clinical and histological resolution of lentigo maligna in more than 50 patients. " 01/01/1989 - "Ten years' experience of treating lentigo maligna with topical azelaic acid."

Related Drugs and Biologics

1.	Metronidazole (Metric)
2.	hydroquinone (Black and White)
3.	Tretinoin (Retinoic Acid)
4.	Doxycycline (Vibramycin)
5.	glycolic acid (glycolate)
6.	adapalene (Differin)
7.	Sulfur
8.	azelaic acid (Azelex)
9.	Sulfacetamide (Bleph)
10.	Isotretinoin (Accutane)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Skin Care
3.	Solid-State Lasers
4.	Palliative Care (Palliative Medicine)
5.	Laser Therapy (Surgery, Laser)