ammonium tungsten antimonate hydroxide oxide

09/01/1986 - "In contrast to HPA-23, DS-500 was equally effective whether given 4 days before or 8 h after the time of infection. "
01/01/1983 - "HPA-23 may interact with certain cells of the lymphoreticular system, preventing infection and, perhaps, the early replication of agent."
09/01/1978 - "Inhibition also occurred when treatment with HPA 23 was started 18 to 24 h after infection in the plaque assay but no effect was seen when HPA 23 was added 48 h after virus inoculation. "
09/01/1986 - "The effect was greatest when the first dose of HPA-23 was given 4 h after injecting scrapie, but it declined rapidly as this interval was increased, and there was virtually no effect 2 days after infection. "
01/01/1985 - "HPA 23, used at 120 mg/kg, can prevent fox rabies when it is administered at the time of infection: this compound has protected two foxes. "

01/01/1986 - "HPA-23 was used in a parallel, multiple dose study in patients with Centers for Disease Control (CDC)-defined AIDS. "
12/01/1990 - "The anti-viral drug HPA-23 (ammonium 21-tungsto-9-antimonate) has been proposed for use in the combat against AIDS. "
09/01/1988 - "An open-label, multicenter clinical trial assessed the tolerance of HPA-23 (ammonium-21-tungsto-9-antimoniate) in patients with acquired immune deficiency syndrome. "
09/01/1988 - "Clinical trial of tolerance of HPA-23 in patients with acquired immune deficiency syndrome."
02/23/1985 - "Antimoniotungstate (HPA 23) treatment of three patients with AIDS and one with prodrome."

01/01/1983 - "In a very long incubation model of scrapie, the course of 12 daily doses of HPA-23 represented less than 3 per cent of the total incubation period. "
01/01/1983 - "Treatment of animals with HPA-23, starting just before injecting scrapie, produced survivors. "
01/01/1983 - "The effects of up to 12 daily doses of HPA-23 (ammonium 5-tungsto-2-antimoniate) on scrapie were studied using five experimental models of the disease, some with widely different incubation times. "
09/01/1986 - "A regime of three daily injections of the inorganic heteropolyanion HPA-23 reduced the effective scrapie dose by more than 99%; i.e., some mice survived peripherally injected doses of 100 50% lethal dose units. "
09/01/1986 - "The effect was greatest when the first dose of HPA-23 was given 4 h after injecting scrapie, but it declined rapidly as this interval was increased, and there was virtually no effect 2 days after infection. "

01/01/1985 - "Ammonium-5-tungsto-2-antimoniate (HPA23) can prevent fox rabies."
01/01/1985 - "HPA 23, used at 120 mg/kg, can prevent fox rabies when it is administered at the time of infection: this compound has protected two foxes. "
01/01/1988 - "As some HPA compounds did produce a therapeutic effect in mice, two of them HPA 23 and HPA 39 were administered to rabies-infected foxes. "

04/01/1976 - "Effect of ammonium 5-tungsto-2-antimoniate on encephalomyocarditis and vesicular stomatitis virus infections in mice."
04/01/1976 - "Ammonium 5-tungsto-2-antimoniate (HPA 23) protected micr partially or completely against two strains of encephalomyocarditis (EMC) virus and one strain of vesicular stomatitis (VSV) virus. "