tetramethylrhodamine isothiocyanate

used for labeling of antibodies with fluorochromes; easily dissolved with DMSO; conjugates with immunoglobulins

Also Known As:

Methanaminium, N-(9-(2-carboxy-4-thiocyanatophenyl)-6-(dimethylamino)-3H-xanthen-3-ylidene)-N-methyl-, chloride; TRITC; rhodamine tetramethylisothiocyanate; Xanthylium, 9-(2-carboxy-4-thiocyanatophenyl)-3,6-bis(dimethylamino)-, chloride

Networked: 48 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - Rhodamines: 466
        tetramethylrhodamine isothiocyanate: 48

Experts

1.	Gaustad, Jon-Vidar: 6 articles (03/2015 - 07/2008)
2.	Rofstad, Einar K: 6 articles (03/2015 - 07/2008)
3.	Simonsen, Trude G: 4 articles (03/2015 - 03/2010)
4.	Karlberg, Ann-Therese: 2 articles (01/2022 - 01/2018)
5.	Karlsson, Isabella: 2 articles (01/2022 - 01/2018)
6.	Ji, Bing: 2 articles (07/2020 - 01/2020)
7.	Li, Yuancheng: 2 articles (07/2020 - 01/2020)
8.	Mao, Hui: 2 articles (07/2020 - 01/2020)
9.	Qian, Weiping: 2 articles (07/2020 - 01/2020)
10.	Wu, Hui: 2 articles (07/2020 - 01/2020)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2018 - "Importantly, in vivo experiments demonstrate the tumor inhibition of mitochondrial targeting UCNP-GQD/TRITC with improved therapeutic efficiency compared with non-targeting UCNP-GQD. " 07/20/2020 - "Costaining tissue sections of the 4T1 mouse mammary tumors using an anti-CD206 antibody and fluorescent dye (TRITC)-labeled Man-IONP showed 94.7 ± 4.5% colocalization of TRITC-Man-IONPs with the anti-CD206 antibody. " 01/01/2020 - "Multiphoton imaging, confocal fluorescence imaging, histological staining and computational analysis were applied to track different types of NPs in tumors at 1, 3 and 24 hours after co-injection of equal amounts of paired NPs, e.g., active targeting FITC-Tf-uIONPs and non-targeting TRITC-uIONPs, or FITC-Tf-IONPs and TRITC-IONPs into the same mice bearing 4T1 mouse mammary tumors. " 03/01/2015 - "Morphologic parameters of tumor vascular networks were assessed from high-resolution transillumination images, and tumor blood supply time and plasma velocities were assessed from first-pass imaging movies recorded after a bolus of 155 kDa tetramethylrhodamine isothiocyanate-labeled dextran had been administered intravenously. " 01/01/2013 - "Vascular morphology was assessed from high-resolution transillumination images, and tumor blood supply was assessed from first-pass imaging movies recorded after a bolus of 155 kDa tetramethylrhodamine isothiocyanate-labeled dextran had been administered intravenously. "
2.	Lymphoma (Lymphomas) 01/01/1981 - "Tissue sections of frozen biopsy specimens obtained from normal and hyperplastic human lymphoid tissues as well as 40 cases of non-Hodgkin's lymphomas were analysed in immunofluorescence tests (using red TRITC and green FITC double-labeling). " 08/01/1980 - "Tissue sections of frozen biopsy specimens obtained from normal and hyperplastic human lymphoid tissues, 33 cases of non-Hodgkin lymphomas as well as various forms of immunoregulatory disorders (angioimmunoblastic and dermatopathic lymphadenopathy) were analysed in immunofluorescence tests (using red TRITC and green FITC double-labelling). "
3.	Herpes Zoster 02/01/2011 - "Following incubation with zona-free porcine oocytes, bound protein was visualized with 20 μg TRITC-avidin/ml using confocal microscopy. " 08/01/1993 - "Sperm-binding to salt-stored zona pellucida, as assayed by FITC and TRITC labeling of antibody-free and antibody-coated spermatozoa incubated with the same zona, was consistently reduced by 60-85% by the five eluted samples tested. "
4.	Breast Neoplasms (Breast Cancer) 06/01/1985 - "The ligands, estradiol-6-carboxymethyloxime-BSA-fluoresceine isothiocyanate and hydroxyprogesteronehemisuccinate-BSA-tetramethylrhodamine isothiocyanate, used for histochemistry, did not bind to either ER or PR and were mainly bound to the membrane fraction of isolated breast cancer cells. " 06/01/2010 - "The pH-PMs with 10wt.% of TRITC could deliver substantially more fluorescence dyes to the target tumor tissue in MDA-MB231 human breast tumor-bearing mice, compared to the control polymeric micelles of PEG-poly(l-lactic acid) (PEG-PLLA). "
5.	Bone Resorption 04/01/2014 - "Tartrate-resistant acid phosphatase (TRAP) staining, pit formation assay with bovine cortical bone slices, and co-staining with tetramethyl rhodamine isothiocyanate (TRITC)-conjugated phalloidin and Hoechst 33258 were performed to determine the number of TRAP-positive cells and bone resorption activity. " 06/01/2013 - "Tartrate-resistant acid phosphatase (TRAP) staining, pit formation assay, and co-staining with tetramethylrhodamine isothiocyanate (TRITC)-conjugated phalloidin and Hoechst 33258 were all performed to determine the number of TRAP-positive cells, bone resorption activity, and the level of apoptosis, respectively. "

Related Drugs and Biologics

1.	Fluorescein-5-isothiocyanate (FITC)
2.	Fluorescein (Funduscein)
3.	isothiocyanic acid
4.	rhodamine isothiocyanate
5.	Propidium (Propidium Iodide)
6.	DAPI
7.	Dextrans (Dextran)
8.	tetramethylrhodamine isothiocyanate
9.	Fluorescent Dyes (Fluorescent Probes)
10.	Phalloidine

Related Therapies and Procedures

1.	Therapeutics
2.	Intravenous Injections
3.	Intradermal Injections