stearylamine

RN given refers to parent cpd

Also Known As:

1-octadecanamine, hydrochloride; 1-octadecanamine, hydrochloride (1:1); 1-octadecylamine; octadecyl ammonium chloride; octadecylamine; octadecylamine hydrochloride; stearamine; stearyl amine; stearylamine hydrochloride; stearylammonium chloride

Networked: 63 relevant articles (5 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - stearylamine: 63

Experts

1.	Ali, Nahid: 5 articles (09/2020 - 09/2004)
2.	De, Manjarika: 4 articles (09/2020 - 07/2008)
3.	Deng, Yihui: 4 articles (11/2019 - 06/2014)
4.	Song, Yanzhi: 4 articles (11/2019 - 06/2014)
5.	Kim, Dukjoon: 3 articles (11/2022 - 08/2009)
6.	Banerjee, Indranil: 2 articles (09/2020 - 03/2018)
7.	Ghosh, Sneha: 2 articles (09/2020 - 03/2018)
8.	Liu, Mingqi: 2 articles (11/2019 - 11/2018)
9.	Liu, Xinrong: 2 articles (11/2019 - 11/2018)
10.	Zhang, Ting: 2 articles (06/2019 - 06/2014)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2019 - "The ultrasonication-triggered interfacial assembly approach was developed to synthesize magnetic Janus amphiphilic nanoparticles (MJANPs) for cancer theranostic applications, where the biocompatible octadecylamine is used as a molecular linker to mediate the interactions between hydrophobic and hydrophilic nanoparticles across the oil-water interface. " 07/01/2020 - ": The rational for this approach is to bring a new approach to cancer treatment with modification of IBU-loaded PLGA NPs with ERS and/or octadecylamine by means of smaller particle size (PS), cationic surface, biocompatible nature, and investigating their selective efficacy on lung cell lines (A549 lung cancer cell and CCD-19Lu normal cell line).Methods: IBU encapsulated PLGA-based NPs were prepared and characterized for physical and solid-state analyses. " 07/01/2020 - "Objective: The purpose of this study was the design ibuprofen (IBU)-loaded unique Eudragit® RS 100 (ERS) and/or octadecylamine modified PLGA nanoparticles (NPs) for cancer treatment.Significance" 07/01/2020 - "Novel approaches to cancer therapy with ibuprofen-loaded Eudragit® RS 100 and/or octadecylamine-modified PLGA nanoparticles by assessment of their effects on apoptosis." 06/03/2013 - "In particular, the in vivo tumor inhibitory efficacy of SA-TSN in MCF-7/ADR induced models was more effective than that of teniposide loaded self-assembled nanocarrier without stearylamine (TSN) and teniposide solution (TS), which verified the effectiveness of SA-TSN in reversal of MDR. "
2.	Malaria 06/15/2019 - "In the present study, a novel material (octadecylamine modified chondroitin sulfate) was synthesized, to fabricate a long acting release meshy gel system as an efficient weapon for protracted warfare to malaria. " 12/14/2015 - "This is the first report to demonstrate that monensin in PEGylated stearylamine (SA) liposome has therapeutic potential against malaria infections. "
3.	Breast Neoplasms (Breast Cancer) 09/15/2017 - "Enhanced efficacy of anti-miR-191 delivery through stearylamine liposome formulation for the treatment of breast cancer cells." 09/15/2017 - "Here, we have developed a stearylamine (SA) based cationic liposome for delivery of miR-191 inhibitor (anti-miR-191), and studied its efficacy in breast cancer cells (MCF-7 and ZR-75-1) in culture. " 06/03/2013 - "Herein, we tried to develope a mitochondria targeted teniposide loaded self-assembled nanocarrier based on stearylamine (SA-TSN) to reverse MDR of breast cancer. " 08/30/2023 - "In the current work, fisetin is complexed for the first time with soy phosphatidylcholine in the presence of cholesterol to form a novel biocompatible phytosomal system entitled "cholephytosomes." To improve fisetin antitumor activity against breast cancer, stearylamine bearing cationic cholephytosomes (mPHY) were prepared and furtherly modified with hyaluronic acid (HPHY) to allow their orientation to cancer cells through their surface exposed phosphatidylserine and CD-44 receptors, respectively. "
4.	Neoplasm Metastasis (Metastasis) 09/01/2020 - "Combining doxorubicin with stearylamine-bearing liposomes elicits Th1 cytokine responses and cures metastasis in a mouse model." 06/01/2014 - "Based on the knowledge that sialic acid is a critical element for tumor development and its receptors are highly expressed on the tumor-associated macrophages (TAMs) which play important roles in the growth and metastasis of tumors, we synthesized a sialic acid-octadecylamine conjugate (SA-ODA) and anchored it on the surface of pixantrone (Pix)-loaded liposomes, to achieve an improved anticancer effect. "
5.	Infections 12/14/2015 - "This is the first report to demonstrate that monensin in PEGylated stearylamine (SA) liposome has therapeutic potential against malaria infections. " 09/01/2004 - "Combination therapy using sodium antimony gluconate in stearylamine-bearing liposomes against established and chronic Leishmania donovani infection in BALB/c Mice."

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	N-Acetylneuraminic Acid (Sialic Acid)
3.	Epirubicin (Ellence)
4.	pixantrone (BBR 2778)
5.	Teniposide (VM 26)
6.	Solutions
7.	Monensin (Coban)
8.	Elements
9.	Cholesterol
10.	Lecithins

Related Therapies and Procedures

1.	Therapeutics
2.	Microspheres (Microsphere)
3.	Intravenous Infusions
4.	Intravenous Administration
5.	Fluid Therapy (Oral Rehydration Therapy)