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sodium bisulfite

has been used externally for parasitic skin diseases and as gastrointestinal antiseptic; structure
Networked: 88 relevant articles (1 outcomes, 5 trials/studies)

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Drug Context: Research Results

Experts

1. Reifenberger, Guido: 5 articles (05/2010 - 11/2006)
2. Wolter, Marietta: 4 articles (05/2010 - 11/2006)
3. Riemenschneider, Markus J: 3 articles (05/2010 - 11/2008)
4. Domschke, Katharina: 2 articles (01/2015 - 08/2014)
5. Tidow, Nicola: 2 articles (01/2015 - 08/2014)
6. Baune, Bernhard T: 2 articles (01/2015 - 08/2014)
7. Deckert, Jürgen: 2 articles (01/2015 - 08/2014)
8. Zwanzger, Peter: 2 articles (01/2015 - 08/2014)
9. Arolt, Volker: 2 articles (01/2015 - 08/2014)
10. Lesch, Klaus-Peter: 2 articles (01/2015 - 08/2014)

Related Diseases

1. Bronchial Spasm
2. Colorectal Neoplasms (Colorectal Cancer)
3. Adenoma (Adenomas)
07/01/2004 - "Sodium bisulfite sequencing of pooled tumor cohorts, used in the isolation of this gene, showed that only a proportion of the adenomas within the pools were methylated; however, expression analysis by quantitative RT-PCR of individual adenoma irrespective of subtype showed the majority (30 of 38; 79%) failed to express this gene relative to normal pituitary. "
06/01/2009 - "Methylation-specific polymerase chain reaction and sodium bisulfite sequencing of these genes show that DCC, but not MBD1, CXXC1, SMAD4 and MBD2, has promoter CpG island methylation in CRC cell lines and tissues {normal mucosa [29.5% (18/61)], adenomas [81.0% (47/58)] and carcinomas [82.7% (62/75)] (P = 8.6 x 10(-9))} that is associated with reduced DCC expression, independent of 18q21 loss analyzed by multiplex ligation-dependent probe amplification. "
07/01/2004 - "Sodium bisulfite sequencing of individual adenomas showed that 6 of 30 (20%) that failed to express pituitary tumor apoptosis gene (PTAG) were methylated; however, genetic change as determined by loss of heterozygosity and sequence analysis was not apparent in the remaining tumors that failed to express this gene. "
05/01/2007 - "To study, in detail, methylation during colorectal cancer development in high-risk adenomas, we developed an assay combining in situ (on-slide) sodium bisulfite modification (SBM) of paraffin-embedded archival tissue sections with absolute quantitative assessment of methylated alleles (AQAMA). "
10/01/2007 - "In stool samples from 36 patients with colorectal neoplasia (7 adenoma, 29 colorectal cancer) and 17 healthy control subjects, isolated DNA was treated with sodium bisulfite and analyzed by methylation-specific polymerase chain reaction with primers specific for methylated or unmethylated promoter sequences of the secreted frizzled-related protein-1 gene. "
4. Breast Neoplasms (Breast Cancer)
5. Allergic Contact Dermatitis

Related Drugs and Biologics

1. chloroprocaine (Nesacaine)
2. 5-Methylcytosine (5 Methylcytosine)
3. Paraffin
4. Lidocaine (Xylocaine)
5. Edetic Acid (EDTA)
6. Cytarabine (Cytosar-U)
7. DNA (Deoxyribonucleic Acid)
8. Chromatin
9. Vitamin K
10. Sulfur Dioxide

Related Therapies and Procedures

1. Intraperitoneal Injections
2. Phacoemulsification
3. Ligation
4. Spinal Injections