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propionylcholine

RN given refers to parent cpd

Also Known As:

propionylcholine chloride; propionylcholine iodide; propionylcholine tosylate

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Momonoki, Yoshie S: 1 article (03/2008)
2.	Oguri, Suguru: 1 article (03/2008)
3.	Yamamoto, Kosuke: 1 article (03/2008)
4.	Huddart, H: 1 article (04/2002)
5.	Wright, T J: 1 article (04/2002)

Related Diseases

1.	Ganglion Cysts (Ganglion) 05/01/1972 - "1. The iontophoretic application of acetylcholine (ACh) on to identified neurones in the buccal ganglion of the mollusc Navanax produced a biphasic or monophasic membrane potential change which was a function of the current intensity and site of ACh application.2. Low iontophoretic currents, 200 msec in duration, applied to the somatic surface facing the neuropile, caused a monophasic potential change of 6-10 sec duration, which had a reversal potential of about - 50 mV, varied with changes in the [Cl](o) of the bathing medium, and was not blocked by the cholinolytics tested.3. ACh applied more distal to the soma, in the neuropile, produced a 1-3 sec monophasic response whose reversal potential was more positive than - 30 mV, varied in amplitude with changes in the [Na](o) of the medium, and was blocked by cholinolytics such as tubocurarine, hexamethonium and atropine.4. With larger iontophoretic currents a biphasic response could be obtained, depolarization followed by hyperpolarization, which represented a superposition of the above monophasic potentials.5. The cholinomimetics propionylcholine and butyrylcholine caused a biphasic response like that to ACh. "
2.	Pain (Aches) 03/01/2008 - "Similar to electric eel AChE, both plant AChEs hydrolyzed acetylthiocholine (or acetylcholine) and propionylthiocholine (or propionylcholine), but not butyrylthiocholine (or butyrylcholine), and their specificity constant was highest against acetylcholine. "
3.	Neuroblastoma 09/15/1995 - "The muscarinic receptor-stimulated mobilisation of calcium ions in SH-SY5Y neuroblastoma cells was measured as function of the concentration of seven muscarinic receptor agonists and partial agonists: carbamoylcholine, acetylcholine, propionylcholine, butyrylcholine, acetylthiocholine, methylfurmethide and tetrametylammonium. "
4.	Contracture 04/01/2002 - "ACh induced concentration-dependent smooth tonic contractures coupled with considerable depolarisation from the normal resting membrane potential of -30.6 mV. The use of choline ester analogues such as carbachol, propionylcholine and butyrylcholine, specific cholinergic agonists such as nicotine, muscarine, bethanecol and pilocarpine and antagonists such as d-tubocurarine, succinylcholine, hexamethomium, atropine, gallamine, pirenzepine and scopolamine indicated that the ACh receptor showed both nicotinic and muscarinic characteristics; the muscarinic activity resembled that of a mammalian M(2)-like receptor. "

Related Drugs and Biologics

1.	butyrylcholine
2.	Acetylcholine (Acetylcholine Chloride)
3.	Cholinergic Agents (Cholinergics)
4.	Tubocurarine (Tubocurarine Chloride)
5.	Carbachol (Carbastat)
6.	Atropine
7.	Acetylthiocholine
8.	Hexamethonium (Hexamethonium Bromide)
9.	Bethanechol (Duvoid)
10.	Cholinergic Antagonists (Anticholinergics)