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alginic acid (sodium alginate)

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marine algal polysaccharide; a linear copolymer consisting mainly of Beta-1,4-linked D-mannuronic acid and alpha-1,4-linked L-glucuronic acid; RN given refers to cpd with unknown MF; xantalgin is a dental impression material

Also Known As:

sodium alginate; alginate; potassium alginate; calcium alginate; Alloid G; Kalrostat; Kalrostat 2; Kaltostat; Vocoloid; Xantalgin; alginic acid, barium salt; alginic acid, calcium salt; alginic acid, copper salt; alginic acid, potassium salt; alginic acid, sodium salt; barium alginate; calginat; copper alginate; poly(mannuronic acid); poly(mannuronic acid), sodium salt; polymannuronic-guluronic acid; sodium calcium alginate

Networked: 1394 relevant articles (110 outcomes, 232 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Høiby, Niels: 13 articles (03/2013 - 08/2002)
2.	Ohman, Dennis E: 12 articles (05/2015 - 06/2002)
3.	Zhao, Xia: 10 articles (01/2016 - 06/2003)
4.	Dumville, Jo C: 9 articles (10/2015 - 01/2011)
5.	Yang, Li: 9 articles (01/2015 - 06/2003)
6.	Wang, Wei: 8 articles (01/2015 - 07/2005)
7.	O'Meara, Susan: 8 articles (01/2015 - 01/2011)
8.	Cohen, Smadar: 8 articles (07/2014 - 11/2002)
9.	Florczyk, Stephen J: 7 articles (10/2015 - 08/2010)
10.	Zhang, Miqin: 7 articles (10/2015 - 08/2010)

Related Diseases

1.	Wounds and Injuries (Trauma) 08/01/2004 - "Foam and alginate dressings are highly absorbent and effective for heavily exuding wounds. " 01/01/2015 - "One study compared NPWT with an alginate dressing in the treatment of open, infected groin wounds. " 04/01/2014 - "This study aims to address several challenges in alginate nanofiber application, including the lack of structural stability in aqueous environment and limited cell attachment as compared to commercial wound dressings, via examining crosslinking techniques. " 09/15/2013 - "In our previous study, a novel alginate-based bilayer film for slow-release wound dressings was successfully developed. " 08/01/2013 - "Present study examines the influence of honey-alginate and alginate matrices on re-epithelialization in keratinocyte (HaCaT) population in a 2-D wound model. "
2.	Gastroesophageal Reflux (GERD) 01/01/1999 - "Aluminium-free alginate demonstrated superior efficacy over placebo in treating recurrent gastro-oesophageal reflux in paediatric patients. " 11/01/2010 - "Na alginate treatment for gastroesophageal reflux disease in preterm infants seems to be safe and effective." 02/01/2011 - "Gastro-oesophageal reflux is common in preterm newborns; at present, no studies have evaluated the efficacy of sodium alginate in this population. " 01/01/1990 - "[Pharmacologic efficacy of sodium alginate suspension on gastro-esophageal reflux in infants and children]." 12/01/2013 - "In a study of 16 patients with GERD, we observed that the alginate-antacid raft localizes to the postprandial acid pocket and displaces it below the diaphragm to reduce postprandial acid reflux. "
3.	Neoplasms (Cancer) 11/01/2003 - "These data suggest that virus dissemination is a potential problem in local viral gene therapy of cancer and that the dissemination could be significantly reduced by the alginate solution without compromising the efficacy of gene therapy." 04/16/2008 - "The present study provides evidence that SPIO-alginate might have the ability to improve the detection of liver tumors as an MR contrast agent, and the efficacy is associated with the SPIO specifically located in Kupffer cells in hepatic sinusoid." 01/01/2016 - "Additionally, current progress in research on immuno-inflammatory, anti-neurodegenerative and anti-tumor activities of alginate derivatives is highlighted. " 04/01/2015 - "Alginate core-shell beads for simplified three-dimensional tumor spheroid culture and drug screening." 09/01/2014 - "NP-loaded alginate carriers, meanwhile, offer a promising strategy for delivery of anticancer drugs to tumor sites in the colon and reducing systemic side effects."
4.	Infection 04/01/1985 - "Thus antibody to alginate may offer strain-dependent protection against chronic lung infection with P. " 01/01/2000 - "There was one infection in the study, occurring in the alginate group. " 01/01/1997 - "There were two infections in the study, both occurring in the alginate group while there was no difference in dressing slippage between the two groups. " 10/01/1993 - "aeruginosa into the exopolysaccharide alginate overproducing strains plays a critical role in the establishment of chronic infection, studies are directed towards understanding the processes underlying this phenomenon. " 04/01/1985 - "Studies on the ability of alginate to act as a protective immunogen against infection with Pseudomonas aeruginosa in animals."
5.	Pressure Ulcer (Bedsore) 10/01/2015 - "To assess the effects of alginate dressings for treating pressure ulcers in any care setting. " 10/01/2015 - "Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. " 10/01/2015 - "Alginate dressings for treating pressure ulcers." 01/01/2015 - "To assess the effects of alginate dressings for treating pressure ulcers in any care setting. " 01/01/2015 - "Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. "

Related Drugs and Biologics

1.	Silver
2.	sodium bicarbonate drug combination magnesium trisilicate aluminium hydroxide alginate (Gaviscon)
3.	Chitosan
4.	Colloids (Colloid)
5.	Capsules
6.	Carboxymethylcellulose Sodium (Polycell)
7.	Omeprazole (Esomeprazole)
8.	Doxorubicin (Adriamycin)
9.	Antacids
10.	Alginates

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Transplantation (Transplant Recipients)
3.	Transplants (Transplant)
4.	Hydrocolloid Bandages (Duoderm)
5.	Negative-Pressure Wound Therapy