platyphylline

from Senecio platyphyllus; RN given refers to (1 alpha)-isomer; structure

Also Known As:

3-ethylidenedodecahydro-5-hydroxy-5,5-dimethyl-1,6- dioxacyclododecino(2,3,4gh)pyrrolizine-2,7-dione; platyphylline hydrochloride; platyphylline, (1alpha,15E)-isomer

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Pyrrolizidine Alkaloids: 290
    - platyphylline: 6
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pyrrolizidine Alkaloids: 290
      - platyphylline: 6

Experts

1.	Braeuning, Albert: 1 article (01/2020)
2.	Creutzenberg, Otto: 1 article (01/2020)
3.	Ebmeyer, Johanna: 1 article (01/2020)
4.	Hengstler, Jan G: 1 article (01/2020)
5.	Hessel-Pras, Stefanie: 1 article (01/2020)
6.	Lampen, Alfonso: 1 article (01/2020)
7.	Rasinger, Josef Daniel: 1 article (01/2020)
8.	Schaudien, Dirk: 1 article (01/2020)

Related Diseases

1.	Body Weight (Weight, Body) 01/01/2020 - "Therefore, a 28-day subacute rat feeding study was performed with six structurally different PA heliotrine, echimidine, lasiocarpine, senecionine, senkirkine, and platyphylline, administered at not acutely toxic doses from 0.1 to 3.3 mg/kg body weight. "
2.	Ulcer 01/01/1991 - "In patients suffering from liver cirrhosis with secondary gastroduodenal ulcers or multiple erosions, the 5-week treatment either with almagel and platyphylline or gastrozepine provided approximately similar results and promoted ulcer and erosion healing in half the cases. "
3.	Trigeminal Neuralgia (Tic Douloureux) 01/01/1996 - "[The use of an analgin-novocaine-platyphylline mixture for arresting the pain attack and treating trigeminal neuralgia]."
4.	Peptic Ulcer (Peptic Ulcers) 01/01/1991 - "In patients suffering from liver cirrhosis with secondary gastroduodenal ulcers or multiple erosions, the 5-week treatment either with almagel and platyphylline or gastrozepine provided approximately similar results and promoted ulcer and erosion healing in half the cases. "
5.	Pain (Aches) 01/01/1996 - "[The use of an analgin-novocaine-platyphylline mixture for arresting the pain attack and treating trigeminal neuralgia]."

Related Drugs and Biologics

1.	heliotrine
2.	senkirkine
3.	senecionine (integerrimine)
4.	lasiocarpine
5.	echimidine
6.	Xanthinol Niacinate (Xavin)
7.	Sodium Nitrite
8.	Procaine (Novocaine)
9.	Dipyrone (Metamizole)
10.	magnesium hydroxide drug combination benzocaine aluminum hydroxide