platycodin

from Platycocon grandiflorum; also see platycodin D & D3

Networked: 6 relevant articles (0 outcomes, 3 trials/studies)

1.	Type 2 Diabetes Mellitus (MODY) 09/01/2014 - "The aim of the current study was to investigate the therapeutic effects and mechanism of platycodin in liver complications of type 2 diabetes. "
2.	Breast Neoplasms (Breast Cancer) 09/01/2016 - "The objective of the present study was to explore the in vitro and in vivo anticancer effects of Platycodin D (PD), derived from Platycodin grandiflorum, on highly metastatic MDA-MB-231 breast cancer cells. " 09/01/2016 - "Platycodin D, a metabolite of Platycodin grandiflorum, inhibits highly metastatic MDA-MB-231 breast cancer growth in vitro and in vivo by targeting the MDM2 oncogene."
3.	Urinary Bladder Neoplasms (Bladder Cancer) 01/01/2021 - "However, few studies on the anti-tumour effects of platycodin against urinary bladder cancer have been reported. "
4.	Prostatic Neoplasms (Prostate Cancer) 01/01/2015 - "Platycodin D (PD), a major saponin derived from Platycodin grandiflorum, exerted cytotoxicity against prostate cancer cell lines (PC3, DU145 and LNCaP cells) with IC₅₀ values in the range of 11.17 to 26.13 μmol/L, whereas RWPE-1 cells (a non-malignant human prostate epithelial cell line) were not significantly affected. "
5.	Obesity 08/01/2005 - "To investigate how and to what extent platycodin saponin (PS) from Platycodi Radix exerts a favorable influence on obesity and hyperlipidemia. "