1-phenyl-3,3-dimethyltriazene (PDT)

12/03/2014 - "NMOFs thus represent a new class of highly potent PDT agents and hold great promise in treating resistant cancers in the clinic. "
01/01/2014 - "As most cancers are being treated with combined therapies, PDT is being integrated into rationally designed regimens that exploit molecular responses to PDT for improved efficacy. "
12/01/2013 - "In vivo PDT experiment based magnetic tumor targeting using IONC-PEG-Ce6 is finally carried out, achieving high therapeutic efficacy with dramatically delayed tumor growth after just a single injection and the MF-enhanced photodynamic treatment. "
04/01/2013 - "The efficacy of ALA-PDT is highly dependent on the photosensitizer (PS) concentration present in the tumor. "
01/22/2013 - "In vivo PDT treatments for deep-seated tumors demonstrated that NIR light-triggered PDT based on the nanoconstructs possessed remarkable therapeutic efficacy with tumor inhibition ratio up to 50% compared with conventional visible light-activated PDT with a noticeable reduced tumor inhibition ratio of 18%. "

01/01/2005 - "The conclusion of this study is that single treatment with topical MAL-PDT is effective for thin actinic keratosis lesions; however, repeated treatment is recommended for thicker or non-responding lesions."
08/01/2011 - "PDT repeated three times at weekly intervals was more effective against actinic keratosis than randomly repeated procedures. "
09/01/2011 - "Two sessions of PDT using ALA with blue light is a moderately effective, well-tolerated treatment of actinic keratoses of the dorsal hand and forearm."
01/01/2004 - "Findings indicate that topical ALA PDT is an effective and safe treatment for multiple actinic keratoses of the face and scalp."
01/01/2004 - "This article reviews the safety and efficacy of large surface ALA-PDT for the treatment of actinic keratoses and photodamage. "

06/01/2012 - "Although after PDT final BCVA was significantly worse from baseline, it may also be beneficial for some patients with neovascular age-related macular degeneration."
10/01/2008 - "Combination IVT treatment with PDT seemed to be more effective for managing neovascular age-related macular degeneration, but long-term analysis failed to demonstrate functional benefits."
10/01/2007 - "Understanding the intracellular signaling mechanisms of apoptosis in PDT may lead to more selective and effective treatment of CNV secondary to age-related macular degeneration."
01/01/2009 - "Combining PDT with the standard age-related macular degeneration protocol is an effective treatment for CCH in terms of resolution of exudative subretinal fluid and recovery of VA. "
07/01/2004 - "Targeted PDT for CNV is feasible and may offer a qualitative improvement in current treatments for patients with age-related macular degeneration. "

09/01/2007 - "PDT i s indicated in theclassical or predominantly classical choroid neovascularization (CNV), anti-VEFG drugs are effective in all forms of exsudative AMD. "
01/01/2007 - "PDT seems to be effective for treating the choroidal neovascularization complicating PDT performed for CSC."
06/01/2006 - "Low power TTT is as effective as standard power in stabilizing or improving vision and reducing overlying exudation in patients with active subfoveal choroidal neovascularization ineligible for PDT."
06/01/2005 - "Although PDT is effective in closing the choroidal neovascularization in FVT, this technique was ineffective in occluding anastomotic vessels and their associated tributaries within the mid- to proximal retina. "
05/01/2003 - "PDT shows efficacy for classic choroidal neovascularization beyond the common indication."

02/01/2011 - "There was a significant reduction in the number of inflammatory acne lesions after PDT, compared to baseline (p<0.05). "
03/01/2010 - "PDT with the treatment regimen employed here may be beneficial for a subgroup of patients with inflammatory acne."
01/01/2007 - "MAL-PDT using IPL and MAL in Asians did not lead to significant improvement of moderate inflammatory acne compared with the control group. "
04/01/2006 - "PDT appeared to be an effective treatment for inflammatory acne vulgaris with no significant differences in the response rate between ALA-PDT and MAL-PDT. "
12/01/2005 - "ALA-PDT with red light was found to be effective in the reduction of the number of inflamed lesions in patients with mild-to-moderate acne vulgaris, with no significant short-term adverse effects."