perfluorotributylamine (FC 43)

02/01/1997 - "Efficacy of perfluorotributylamine/pluronic F-68 stem-emulsion (FC43se) against reperfusion injury in ischemic rabbit lungs."
01/01/1994 - "To evaluate the efficacy of a perflurocarbon emulsion (Fluosol: FC-43) for protecting preserved lungs from ischemic reperfusion injuries, we employed an isolated canine left lung reperfusion model. "

10/01/1989 - "This test improved the detection rate of FTBA for the liver dysfunction and reflects the severity of the diseases. "
01/01/1994 - "Comparison between FTBA, PTBA and other liver function tests in various liver diseases from this study the PTBA was not statistically significant superior to FTBA. "

11/01/2018 - "In this study, it is originally discovered that perfluorotributylamine-based albumin nanoparticles (PFTBA@HSA) possess excellent platelet inhibiting abilities, which then selectively disrupt the tumor vessel barrier, resulting in a remarkably enhanced intratumoral drug accumulation. "
05/10/2019 - "The crude extract, fractions FTBa, FTBc, FTBd as well as compounds 5 and 6 revealed cytotoxicity towards the 9 tested cancer cell lines. "
06/01/1982 - "The tumor-bearing rats for 10 days after implantation were randomly divided into 4 groups; a control group, a Fluosol-43 treatment group, a BCNU treatment group, and a Fluosol-43 plus BCNU treatment group. "
01/01/2023 - "Perfluorotributylamine-Loaded Albumin Nanoparticles Downregulate Platelet-Derived TGFβ to Inhibit Tumor Metastasis."
11/01/2019 - "In this study, we screened an array of perfluorocarbon compounds, reporting that albumin-based perfluorotributylamine nanoparticles (PFTBA@Alb) can effectively increase the permeability of tumor blood vessels, and no distinct side effects were found on normal blood vessels. "

10/01/1983 - "Thus, while intense levels of hypoxia are required to stimulate the extrarenal production of Ep, these data suggest that as Fluosol-43 is taken up by the hepatic macrophages, Ep production by these cells is stimulated."
01/01/2020 - "In our previous studies, we demonstrated that perfluorotributylamine (PFTBA) could provide short term oxygen supply to Schwann cells (SCs) and counteract the detrimental effects of hypoxia on SCs during the early stages of nerve injury. "
03/01/1980 - "Tissue hypoxia, responsible for stimulation of glycolytic pathway of carbohydrate metabolism, was apparently developed due to transfer of inadequate amount of oxygen by perfluorotributylamine."
02/01/1985 - "After splenectomy and extensive perfluorotributylamine exchange transfusion, steady-state spectral scans were obtained in Soret and visible wave-length regions during O2 ventilation, during subsequent exposure to O2-enriched gases containing 1, 3, or 5% CO, and finally after N2 anoxia. "
02/01/1983 - "The relative performance of whole blood and saline, a balanced salt-albumin solution, and Fluosol-43 were compared in an experimental animal model of combined hypoxia and hypotension. "

01/01/1995 - "When examined 1 day after a 90-minute interval of ischemia, oxygenated FTBA-filled eyes maintained 45% and 57% of the preischemic ERG a- and b-wave amplitudes, respectively, compared to a 5% and 3% retention of wave amplitudes in oxygenated BSS-filled eyes. "
01/01/1985 - "This study reports an assessment of a method of intestinal protection by the intraluminal administration of an oxygenated perfluorochemical, perfluorotributylamine, or gaseous oxygen in an attempt to provide oxygen for mucosal cells rendered ischemia. "
12/01/1996 - "Langendorff hearts perfused at 37 degrees C with the perfluorochemical emulsion Fluosol-43 were subjected to 15 min and 30 min of zero-flow ischemia and to 15 min of low-flow ischemia (coronary perfusion pressure = 20 mmHg) followed by 65 min of reperfusion (control, Group I). "
01/01/1995 - "Over a 10- or 30-minute period of ischemia, during which electroretinographic (ERG) responses were recorded, FTBA-filled eyes and BSS-filled eyes showed decreases in the a- and b-wave amplitudes. "
08/01/1997 - "The effect of thromboxane A2 synthetase inhibitor (OKY-046) on myocardial metabolism and contractility during ischemia and reperfusion was examined by the phosphorus 31-nuclear magnetic resonance (31P-NMR) in Langendorff rabbit hearts with use of an artificial blood substitute, perfluorochemical emulsion Fluosol-43. "