nocobactins
lipid-soluble iron-chelating product isolated from Nocardia asteroides grown under conditions of iron deficiency; RN given refers to nocobactin NA; structure
Also Known As:
nocobactin NA
Networked: 2
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Sakagami, Hiroshi:
2 articles
(03/2007 - 01/2005)
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2. | Chien, Chien-Huan:
1 article
(03/2007)
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3. | Kanegae, Haruhide:
1 article
(03/2007)
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4. | Kawase, Masami:
1 article
(03/2007)
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5. | Kobayashi, Masaki:
1 article
(03/2007)
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6. | Fukai, Toshio:
1 article
(01/2005)
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7. | Hoshino, Yasutaka:
1 article
(01/2005)
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8. | Ishihara, Mariko:
1 article
(01/2005)
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9. | Ishikawa, Jun:
1 article
(01/2005)
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10. | Mikami, Yuzuru:
1 article
(01/2005)
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Related Diseases
1. | Neoplasms (Cancer)
01/01/2005
- " Nocobactins NA-a (NBNAa) and NA-b (NBNAb) showed higher cytotoxic activity against human tumor cell lines (HSC-2, HSC-3, HL-60) than against normal human cells (gingival fibroblast, pulp cell, periodontal ligament fibroblast), yielding tumor specificity indices (TS) of 80.0 and 43.9, respectively. " 03/01/2007
- " Flavonoids, coumarins, tannins, ketones and other synthetic compounds showed low to moderate tumor-specific cytotoxicity against human OSCC cell lines as compared with normal human oral cells (gingival fibroblast, pulp cell, periodontal ligament fibroblast), whereas anthracyclines, nocobactins and cyclic alpha, beta-unsaturated compounds showed much higher tumor-specific cytotoxicity. "
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