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nitrocaphane

structure

Also Known As:

AT 1258

Networked: 6 relevant articles (2 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Mustard Compounds: 3
      - Nitrogen Mustard Compounds: 2
        nitrocaphane: 6

Related Diseases

1.	Trophoblastic Neoplasms (Trophoblastic Tumor) 12/01/1998 - "The aim of this study was to investigate the efficacy of nitrocaphanum (AT 1258) in combination with 5-fluorouracil (5-FU) in patients with gestational trophoblastic tumors (GTT). " 04/01/1996 - "To evaluate the effectiveness, side effects and long term result of combination protocol of 5-fluorouracil (5-FU) and nitrocaphane (AT1258) on patients with malignant trophoblastic tumor. " 12/01/1988 - "[Combined treatment of malignant trophoblastic tumor with 5-fluorouracil and nitrocaphane]." 04/01/1996 - "[Combination chemotherapy of 5-fluorouracil and nitrocaphane for the treatment of malignant trophoblastic tumor]."
2.	Neoplasms (Cancer) 11/01/1989 - "Six patients with MTX-CF resistant tumors subsequently achieved complete remission with intravenous infusion of KSM and/or AT 1258. "
3.	Hyperthermia 07/01/1989 - "HEp-2 cells were treated with hyperthermia (39-44 degrees C) and nitrocaphane (NC) at various time intervals. " 07/01/1989 - "Enhancement of nitrocaphane cytotoxicity by hyperthermia in vitro." 01/01/1989 - "Cytotoxic effect of hyperthermia combined with Nitrocaphane (NC) on HEp-2 cells was detected by colony formation assay. " 01/01/1989 - "[Cytotoxic effect of hyperthermia and nitrocaphane on malignant HEp-2 cells]."

Related Drugs and Biologics

1.	Fluorouracil (Carac)

Related Therapies and Procedures

1.	Intravenous Infusions
2.	Combination Drug Therapy (Combination Chemotherapy)