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maleamic acid

structure

Also Known As:

maleic acid monoamide

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Maleates: 3
        maleamic acid: 4

Experts

1.	An, Ming: 1 article (11/2017)
2.	Yao, Lan: 1 article (11/2017)
3.	Zhang, Anqi: 1 article (11/2017)

Related Diseases

1.	Neoplasms (Cancer) 10/01/1991 - "Efficacy of 5-fluorouracil in combination with methoxyphenyl maleamic acid in murine tumors." 11/28/2017 - "Reversing the undesirable pH-profile of doxorubicin via activation of a di-substituted maleamic acid prodrug at tumor acidity." 11/28/2017 - "The acid-labile behavior of di-substituted maleamic acid (DMA) and its equilibrium with di-substituted maleimide (DMI) are exploited to build an ultra acid-sensitive, small molecule prodrug that can be activated by tumor extracellular pH (pHe) in the range of 6.5-6.9. "
2.	Ascites 03/01/1991 - "The anti-tumour effects of methoxyphenyl maleamic acid (MPMA) and cytotoxic drugs, in combination were investigated on P388 leukaemia and S180 (ascites) tumours. " 10/01/1991 - "Combination chemotherapy studies were carried out in vivo against sarcoma 180 (ascites)(S180) and Ehrlich (ascites) carcinoma (EAC) tumours using cytotoxic drugs and methoxyphenyl maleamic acid (MPMA), an intermediate in the synthesis of pyrrolidine-nitrogen-mustards. "
3.	Sarcoma 180 10/01/1991 - "Combination chemotherapy studies were carried out in vivo against sarcoma 180 (ascites)(S180) and Ehrlich (ascites) carcinoma (EAC) tumours using cytotoxic drugs and methoxyphenyl maleamic acid (MPMA), an intermediate in the synthesis of pyrrolidine-nitrogen-mustards. "
4.	Carcinoma (Carcinomatosis) 10/01/1991 - "Combination chemotherapy studies were carried out in vivo against sarcoma 180 (ascites)(S180) and Ehrlich (ascites) carcinoma (EAC) tumours using cytotoxic drugs and methoxyphenyl maleamic acid (MPMA), an intermediate in the synthesis of pyrrolidine-nitrogen-mustards. "
5.	Allergic Contact Dermatitis 12/01/1982 - "These are the first documented cases of allergic contact dermatitis from dodecyl maleamic acid." 12/01/1982 - "Allergic contact dermatitis from dodecyl maleamic acid in Curad adhesive plastic bandages."

Related Drugs and Biologics

1.	Fluorouracil (Carac)
2.	Nitrogen
3.	pyrrolidine
4.	Prodrugs
5.	Plastics
6.	Doxorubicin (Adriamycin)
7.	Acids
8.	maleimide

Related Therapies and Procedures

1.	Combination Drug Therapy (Combination Chemotherapy)