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isovaleric acid

structure

Also Known As:

3-methylbutyrate; 3-methylbutyric acid; 3-methylbutanoic acid

Networked: 53 relevant articles (5 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Hemiterpenes: 4
      - isovaleric acid: 53
- Carboxylic Acids: 973
  - Acyclic Acids
    - Valerates: 135
      - Pentanoic Acids: 1
        isovaleric acid: 53
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Valerates: 135
      - Pentanoic Acids: 1
        isovaleric acid: 53

Experts

1.	Akayzin, E S: 2 articles (01/2019 - 01/2018)
2.	Metelev, A S: 2 articles (01/2019 - 01/2018)
3.	Leipnitz, Guilhian: 2 articles (03/2009 - 08/2008)
4.	Seminotti, Bianca: 2 articles (03/2009 - 08/2008)
5.	Wajner, Moacir: 2 articles (03/2009 - 08/2008)
6.	Bolen, Jessica: 1 article (06/2022)
7.	Chou, Maxwell: 1 article (06/2022)
8.	DeMarzo, Danielle: 1 article (06/2022)
9.	Enchautegui-Colon, Yazmin: 1 article (06/2022)
10.	Lin, Hsin-Ti: 1 article (06/2022)

Related Diseases

1.	Body Weight (Weight, Body) 01/01/1977 - "14C-Labelled D-penicillamine [D-(--)-alpha-amino-beta-mercapto-isovaleric acid; Trolovol] was administered to rats in doses of 10 to 50 mg/kg body weight orally or i.v. A dose of 0.25 mg per rat was used for intra-articular injection (knee joint). " 01/01/2019 - "In vivo studies revealed that diet supplementation with a mixture of essential oils and organic acids improved the final body weight and ADG of piglets (P < 0.05), increased the concentration of serum complement 4 (P < 0.05), and enhanced the fecal level of isovaleric acid (P < 0.05) compared with controls on day 28. "
2.	Stomach Neoplasms (Stomach Cancer) 08/01/2023 - " content of isobutyric acid and isovaleric acid in the WD-3 group was higher than that in the healthy control group(P=0.037,P=0.004).Conclusion WD-3 Mixture may increase the relative abundance of Bifidobacteria and Coprococcus and the content of isobutyric acid and isovaleric acid to alter the intestinal microecology,thereby improving the efficacy of immunotherapy for gastric cancer. "
3.	Osteoporosis 01/01/2021 - "Isovaleric acid ameliorates ovariectomy-induced osteoporosis by inhibiting osteoclast differentiation."
4.	Insulin Resistance 04/01/2023 - "The reprogramming of gut microbiota structure and abundance and the reduction of fecal levels of SCFAs, including acetic acid, butyric acid, isovaleric acid, caproic acid, and isobutyric acid, by melatonin may be beneficial for enhancing insulin sensitivity and lowering FBG, which were verified by the results of correlation analysis between acetic acid or total SCFAs and HOMA-IR and FBG. "
5.	Inflammation (Inflammations) 05/01/2022 - "Isovaleric acid was positively and significantly correlated with Lactobacillus, which all contributing to the improvement in glucose level, systemic inflammation and cognitive function in diabetic rats. "

Related Drugs and Biologics

1.	isobutyric acid
2.	Acids
3.	Volatile Oils (Essential Oils)
4.	Complement C4 (Complement Component 4)
5.	Butyric Acid (Butanoic Acid)
6.	Acetic Acid (Vinegar)
7.	hexanoic acid (hexanoate)
8.	Melatonin
9.	Glucose (Dextrose)
10.	n-pentanoic acid (valeric acid)

Related Therapies and Procedures

1.	Ovariectomy (Oophorectomy)
2.	Immunotherapy
3.	Mediterranean Diet
4.	Intra-Articular Injections