guar gum (guaran)

bulk-forming appetite depressant; water-soluble component is guaran; see also record for locust bean gum (supercol); CtManS gene codes for the mannan synthase and alpha-galactosyltransferase adds galactosyl residues

Also Known As:

Networked: 176 relevant articles (20 outcomes, 38 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Krishnaiah, Y S R: 3 articles (04/2005 - 12/2002)
2.	Satyanarayana, V: 3 articles (04/2005 - 12/2002)
3.	Bakker, Barbara M: 2 articles (01/2015 - 01/2014)
4.	Gerding, Albert: 2 articles (01/2015 - 01/2014)
5.	Pathak, Kamla: 2 articles (01/2015 - 11/2012)
6.	Reijngoud, Dirk-Jan: 2 articles (01/2015 - 01/2014)
7.	Groen, Albert K: 2 articles (01/2015 - 01/2014)
8.	Bleeker, Aycha: 2 articles (01/2015 - 01/2014)
9.	den Besten, Gijs: 2 articles (01/2015 - 01/2014)
10.	Havinga, Rick: 2 articles (01/2015 - 01/2014)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2006 - "Cross-linked guar gum microspheres: a viable approach for improved delivery of anticancer drugs for the treatment of colorectal cancer." 01/01/2006 - "In the present work, guar gum microspheres containing methotrexate (MTX) were prepared and characterized for local release of drug in the colon, which is a prerequisite for the effective treatment of colorectal cancer. " 11/01/2009 - "In this way, 5-fluorouracil loaded guar gum microspheres have shown promising results in the management of colorectal cancer, warranting thorough in vivo study for scale up technology." 06/01/2006 - "The purpose of this study was to develop a biodegradable drug platform composed of chitosan and guar gum and to explore the possibility of using it for local adjuvant or neoadjuvant therapy of colorectal cancer. " 11/01/2009 - "The present investigation is aimed to develop a new formulation containing chemically crosslinked guar gum microspheres loaded with 5-fluorouracil for targeting colorectal cancer. "
2.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 08/01/2002 - "High-fiber diet supplementation in patients with irritable bowel syndrome (IBS): a multicenter, randomized, open trial comparison between wheat bran diet and partially hydrolyzed guar gum (PHGG)." 03/01/2006 - "Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome." 06/01/2005 - "Treatment effects of partially hydrolyzed guar gum on symptoms and quality of life of patients with irritable bowel syndrome. " 01/01/2001 - "[Partially hydrolyzed guar gum: a fiber as coadjuvant in the irritable colon syndrome]." 11/01/2011 - "Stool consistency and abdominal pain in irritable bowel syndrome may be improved by partially hydrolysed guar gum."
3.	Pruritus (Itching) 04/01/2000 - "Guar gum treatment-induced changes of the pruritus score and serum bile acid concentrations were significantly related (p<0.01). " 04/01/2000 - "Guar gum diminished or prevented worsening of pruritus, while in the placebo group pruritus was enhanced (p<0.05). " 04/01/2000 - "Guar gum relieved the intensity of pruritus without any side effects and prevented the rise in serum bile acid concentration in this placebo-controlled and double-blind study of patients with intrahepatic cholestasis of pregnancy." 04/01/2000 - "Oral guar gum, a gel-forming dietary fiber relieves pruritus in intrahepatic cholestasis of pregnancy." 05/01/1998 - "Forty-eight pregnant women with cholestasis and pruritus were randomized double-blind to guar gum and placebo until the time of delivery, and 20 healthy pregnant women were used as control subjects. "
4.	Abdominal Pain (Pain, Abdominal) 01/14/2013 - "Partially hydrolyzed guar gum in pediatric functional abdominal pain." 11/01/2011 - "Stool consistency and abdominal pain in irritable bowel syndrome may be improved by partially hydrolysed guar gum." 01/14/2013 - "To assess the effects of partially hydrolyzed guar gum (PHGG) diet supplement in pediatric chronic abdominal pain (CAP) and irritable bowel syndrome (IBS). " 12/01/2010 - "Treatment with partially hydrolyzed guar gum is as effective as lactulose treatment in relieving stool withholding and constipation-associated abdominal pain, and its use improves stool consistency. "
5.	Intrahepatic Cholestasis 04/01/2000 - "Forty-eight patients with intrahepatic cholestasis of pregnancy were randomized double-blind to receive either guar gum or placebo until delivery. " 04/01/2000 - "Guar gum relieved the intensity of pruritus without any side effects and prevented the rise in serum bile acid concentration in this placebo-controlled and double-blind study of patients with intrahepatic cholestasis of pregnancy." 04/01/2000 - "Oral guar gum, a gel-forming dietary fiber relieves pruritus in intrahepatic cholestasis of pregnancy." 05/01/1998 - "We conclude that in intrahepatic cholestasis of pregnancy and pruritus, guar gum treatment is beneficial in relieving pruritus, even although indicators of cholestasis are only partially reduced." 05/01/1998 - "Our aim was to investigate whether intestinal binding of bile acids by guar gum, a dietary fibre, relieves cholestasis and pruritus in intrahepatic cholestasis of pregnancy. "

Related Drugs and Biologics

1.	pectin
2.	Cholesterol
3.	Lipids
4.	Glucose (Dextrose)
5.	Tablets
6.	Lactulose (Duphalac)
7.	Fluorouracil (Carac)
8.	Cholestyramine Resin (Questran)
9.	Tinidazole
10.	Methotrexate (Mexate)

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Fluid Therapy (Oral Rehydration Therapy)
3.	Enteral Nutrition (Feeding, Tube)
4.	Nephrectomy
5.	Neoadjuvant Therapy