glaziovine

a proaporphine alkaloid isolated from Ocotea glaziovii (Lauraceae) found to be similar in activity as an anxiolitic drug to diazepam; structure; RN given refers to (S)-isomer

Also Known As:

glaziovine, (+-)-isomer

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Benzylisoquinolines: 151
    - Aporphines: 10
      - glaziovine: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - Benzylisoquinolines: 151
        Aporphines: 10
        glaziovine: 3
  - 4 or More Rings Heterocyclic Compounds
    - Aporphines: 10
      - glaziovine: 3

Experts

1.	Carrero, Julio César: 1 article (04/2020)
2.	Díaz-Godínez, César: 1 article (04/2020)
3.	Herbert-Pucheta, José Enrique: 1 article (04/2020)
4.	Ontiveros-Rodríguez, Julio C: 1 article (04/2020)
5.	Ríos-Valencia, Diana G: 1 article (04/2020)
6.	Zepeda-Vallejo, L Gerardo: 1 article (04/2020)

Related Diseases

1.	Amebiasis (Amoebiasis) 04/01/2020 - "This study supports the idea that aporphine alkaloids from A. purpurea, mainly (+)-(R)-glaziovine (4: ), could contribute to the development of new formulations for the treatment of amoebiasis. "
2.	Ulcer 01/01/1978 - "The anti-ulcer effect of glaziovine, a major psychotropic alkaloid isolated from Ocotea glaziovii (Laureaceae) and belonging to a new chemical class, has been studied in different types of experimentally induced ulcers in the guinea-pig and the rat. "
3.	Biliary Fistula 06/01/1977 - "The high amount of radioactivity found in the small intestine as well as that found in bile obtained from a biliary fistula demonstrates that glaziovine is excreted both via the bile and via urine in not dissimilar amounts at least in dogs. "

Related Drugs and Biologics

1.	Alkaloids
2.	aporphine