formononetin

12/01/2017 - "Therefore, the results of the current study demonstrated that formononetin ameliorated mast cell-mediated allergic inflammation."
12/01/2023 - "We further expanded on formononetin's putative mode of action in reducing airway inflammation by modifying epithelial barrier dysfunction. "
12/01/2023 - "As a result, we set out to investigate the effects of formononetin on airway inflammation and epithelial barrier repair in house dust mite (HDM)-induced asthmatic mice. "
01/01/2022 - "Overall, our findings revealed that formononetin increased angiogenesis, reduced oxidative stress and inflammation, thus promoting flap survival. "
01/01/2022 - "Using immunohistochemical staining and western blot, we found that formononetin significantly reduced oxidative stress and inflammation. "

06/03/2023 - "Thus, detailed studies based on clinical trials are required to explore the potential role of formononetin in cancer prevention and treatment."
03/22/2017 - "The aim of the present study was to investigate the anti-tumor effects of formononetin on BCa cells and its potential molecular mechanism. "
01/01/2014 - "More interestingly, in the in vivo studies, formononetin showed a noticeable inhibition of tumor growth in recipient mice. "
12/01/2023 - "Formononetin effectively plays a significant role in inhibiting cell proliferation, invasion, and metastatic abilities of cancer cells by targeting major signaling pathways at the junction of interconnected pathways. "
12/01/2023 - "The potential role of formononetin in cancer treatment: An updated review."

01/01/2012 - "The present study shows that formononetin increases soluble-AβPPα (sAβPPα) secretion and thus protects human-AβPP Swedish mutation cell (N2a-AβPP cell) from hypoxia-induced apoptosis. "
01/01/2012 - "Formononetin protects neurons against hypoxia-induced cytotoxicity through upregulation of ADAM10 and sAβPPα."
02/05/2022 - "Among them, six (except formononetin) protected brain endothelial cells against OGD/R injury in a concentration-dependent manner (20-120 μM; P < 0.01-0.05) and downregulated the expression of hypoxia-inducible factor-1α (P < 0.01) involved in the pathogenic mechanisms triggered by stroke. "
09/01/2019 - "Effects and significance of formononetin on the expression levels of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in mouse cervical cancer tissue were investigated. "
01/01/2016 - "Formononetin, an active compound of Astragalus membranaceus (Fisch) Bunge, inhibits hypoxia-induced retinal neovascularization via the HIF-1α/VEGF signaling pathway."

01/01/2018 - "Collectively, our study for the first time confirmed the protective effects of formononetin on DSS-induced acute colitis via inhibiting the NLRP3 inflammasome pathway activation."
01/01/2018 - "In this present study, we aimed to explore the protective effects of formononetin on dextran sulfate sodium- (DSS-) induced acute colitis. "
01/01/2018 - "Furthermore, in the foundation of administrating MCC950 to inhibit activation of NLRP3 inflammasome, we failed to observe the protective effects of formononetin on acute colitis in mice. "
01/01/2018 - "Corrigendum to "Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway"."
01/01/2018 - "Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway."

03/01/2014 - "Protective effects of sulphonated formononetin in a rat model of cerebral ischemia and reperfusion injury."
01/01/2020 - "Formononetin ameliorates myocardial ischemia/reperfusion injury in rats by suppressing the ROS-TXNIP-NLRP3 pathway."
05/01/2022 - "To explore the potential mechanism of action of formononetin in cerebral ischemia-reperfusion injury with regard to the JAK2/STAT3 signaling pathway. "
05/01/2022 - "However, the anti-inflammatory effect of formononetin in cerebral ischemia-reperfusion injury has not been reported. "
12/01/2018 - "Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation."