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flunisolide (AeroBid)

Subscribe to New Research on flunisolide

searcher's request; references & indexing include acetate; RN given refers to (6alpha,11beta,16alpha)-isomer; structure; flunisolide HFA is a formulation of flunisolide using hydrofluoroalkane (HFA) as propellant, developed to comply with the mandated worldwide phase-out of ozone-depleting chlorofluorocarbon (CFC) propellants

Also Known As:

AeroBid; Nasalide; Nasarel; 6 alpha-fluorodihydroxy-16 alpha,17 alpha-isopropylidenedioxy-1,4-pregnadiene-3,20- dione; Apo-Flunisolide; Apotex Brand of Flunisolide; Boehringer Ingelheim Brand of Flunisolide; Dermapharm Brand of Flunisolide; Elan Brand 1 of Flunisolide; Elan Brand 2 of Flunisolide; Forest Brand of Flunisolide; Inhacort; Ivax Brand of Flunisolide; RS-3999; Ratiopharm Brand of Flunisolide; Rhinalar; Roche Brand of Flunisolide; Syntaris; flunisolide HFA; flunisolide hemihydrate, (6alpha,11beta,16alpha)-isomer; flunisolide hydrofluoroalkane; flunisolide, (6beta,11beta,16alpha)-isomer; ratio-Flunisolide; 6 alpha-fluoro-11 beta,16 alpha,17,21- tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16, 17-acetal with acetone

Networked: 151 relevant articles (37 outcomes, 47 trials/studies)

Relationship Network

Drug Context: Research Results

Polycyclic Compounds: 56
- Steroids: 18537
  - Fluorinated Steroids: 24
    - Fluocinolone Acetonide: 282
      - flunisolide: 151
  - Pregnanes: 3
    - Pregnadienes
      - Fluocinolone Acetonide: 282
        flunisolide: 151

Experts

1.	Kantar, Ahmad: 3 articles (02/2014 - 01/2006)
2.	Ciprandi, G: 3 articles (04/2011 - 10/2007)
3.	Capasso, M: 3 articles (04/2011 - 10/2007)
4.	Varricchio, A: 3 articles (04/2011 - 10/2007)
5.	Varricchio, A M: 3 articles (04/2011 - 10/2007)
6.	De Lucia, A: 3 articles (04/2011 - 10/2007)
7.	Newman, Kenneth: 3 articles (11/2005 - 06/2002)
8.	Tashkin, Donald P: 2 articles (03/2015 - 03/2003)
9.	Melani, Andrea S: 2 articles (05/2014 - 07/2012)
10.	Newman, Kenneth B: 2 articles (10/2011 - 03/2002)

Related Diseases

1.	Asthma (Bronchial Asthma) 05/01/2004 - "These studies indicate that flunisolide HFA is effective in controlling asthma. " 03/01/1997 - "For patients with asthma that was stabilized by 2 inhalations of flunisolide (500 microg) bid, switching to 4 inhalations (1000 microg) qd in either the morning or evening is effective in maintaining asthma control. " 03/01/1982 - "Flunisolide aerosol was shown to be effective and safe in controlling asthma in children who were candidates for oral steroid therapy." 03/01/2015 - "The data indicate that flunisolide HFA is a safe and effective maintenance therapy for asthma patients. " 11/01/2001 - "Flunisolide may provide a safe option for patients with asthma requiring long-term inhaled corticosteroid therapy."
2.	Rhinitis 01/01/2002 - "In 20 patients with allergic rhinitis and symptoms of daytime sleepiness, flunisolide significantly improved sleep quality and congestion but daytime sleepiness was not significantly improved. " 07/01/1985 - "Intranasal flunisolide is an effective treatment for allergic rhinitis. " 06/01/1980 - "Flunisolide: a review of its pharmacological properties and therapeutic efficacy in rhinitis." 07/01/1982 - "Flunisolide spray is a safe and effective modality for the treatment of seasonal and perennial rhinitis." 07/14/1979 - "The results show that flunisolide is effective and safe for the treatment and prophylaxis of perennial rhinitis in children."
3.	Seasonal Allergic Rhinitis (Hay Fever) 11/01/1976 - "On the basis of physician interviews and daily symptom dairy scores, patients receiving flunisolide showed significant improvement of hay fever symptoms when compared to their counterparts receiving vehicle. " 01/01/1995 - "Hay fever patients can now get Syntaris Nasal Spray without prescription." 01/01/1994 - "[Clinical and rhino-manometric evaluation of flunisolide in treatment of seasonal allergic rhinitis]." 07/01/1985 - "Global evaluation demonstrated control of overall hayfever severity for N (nasal flunisolide) but not for O (oral flunisolide). " 07/01/1985 - "Ninety-nine patients with ragweed hayfever for greater than or equal to 2 years and positive prick skin tests to ragweed were randomly allocated to one of three treatment groups: 0 = oral flunisolide 500 micrograms b.i.d. "
4.	Respiratory Sounds (Crackle) 09/01/1999 - "At first follow-up visit 3 weeks after esophageal pH studies infants treated with an H2RA and those who did not have GER but continued with daily wheezing were started on flunisolide nasal solution (0.025%) delivered by nebulizer (125 mcg t.i.d.). " 05/01/1996 - "Flunisolide significantly improved symptom scores of wheezing and cough. " 05/01/1996 - "This study indicates that nebulized flunisolide may be an effective treatment for infants with recurrent wheezing and cough." 03/01/1982 - "Most symptom scores were statistically significantly better in flunisolide-treated than in placebo-treated patients; these included severity of wheezing (P = .01), chest tightness (P = .01) and shortness of breath (P = .02), and frequency (P = .001) and severity of asthma attacks (P = .03). " 11/01/2000 - "Nocturnal wheezing and nocturnal albuterol inhaler use was higher among patients receiving flunisolide than those receiving placebo on day 24 (48% versus 18% for nocturnal wheezing, P =.01; mean difference 30%, 95% CI 11% to 49%; 3.8 versus 1.4 nocturnal albuterol puffs, P =.03; mean difference 2.4 puffs, (95% CI 0.2 to 4). "
5.	Nasal Obstruction 01/01/1979 - "The results show flunisolide to be significantly superior to placebo in relieving sneezing, nasal obstruction and postnasal drip, as well as improving the quality of sleep and everday life. " 11/01/1988 - "For example, when flunisolide is given to a patient with allergic rhinitis, the reduction of nasal obstruction and edema can be easily visualized." 10/01/1989 - "A prospective, randomized study comparing the effectiveness of two nasal steroid sprays, flunisolide and beclomethasone dipropionate, in the treatment of nasal obstruction associated with allergic or vasomotor rhinitis has been conducted at New York University Medical Center-Bellevue Hospital. " 02/01/2009 - "Six of these studies demonstrated significant efficacy of various nasal steroids (mometasone, beclomethasone, flunisolide) in improving nasal obstruction symptoms and in reducing adenoid size, as measured with symptom scores and fiber-optic nasopharyngeal endoscopy, respectively. " 05/01/1997 - "Intranasal fluticasone propionate has shown clinical efficacy similar to that of other intranasal corticosteroids, including beclomethasone (administered at up to a 2-fold higher dosage than fluticasone), budesonide, flunisolide and triamcinolone acetonide, and provides greater relief from nasal symptoms (including nasal blockage) than antihistamine agents and intranasal sodium cromoglycate. "

Related Drugs and Biologics

1.	Beclomethasone (Beclometasone)
2.	flunisolide (AeroBid)
3.	Budesonide (Pulmicort)
4.	Adrenal Cortex Hormones (Corticosteroids)
5.	fluticasone (Cutivate)
6.	Albuterol (Salbutamol)
7.	Cromolyn Sodium (Cromoglicic Acid)
8.	Steroids
9.	Triamcinolone Acetonide (Azmacort)
10.	mometasone furoate (mometasone)

Related Therapies and Procedures

1.	Nebulizers and Vaporizers (Inhaler)
2.	Intranasal Administration
3.	Metered Dose Inhalers (Metered Dose Inhaler)
4.	Respiratory Therapy (Therapy, Respiratory)
5.	Aftercare (After-Treatment)