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dioxopromethazine

RN given refers to parent cpd; structure

Also Known As:

Prothanon; dioxopromethazine monohydrochloride; 10H-Phenothiazine-10-ethanamine,N,N,alpha-trimethyl-,5,5-dioxide

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Propylamines: 1
    - Promethazine: 642
      - dioxopromethazine: 4
- Sulfur Compounds: 278
  - Phenothiazines: 506
    - Promethazine: 642
      - dioxopromethazine: 4
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Phenothiazines: 506
      - Promethazine: 642
        dioxopromethazine: 4

Related Diseases

1.	Seasonal Allergic Rhinitis (Hay Fever) 02/02/1970 - "[9,9-dioxopromethazine (Prothanon) at the trial in hay fever]."
2.	Photoallergic Dermatitis (Photoallergy) 09/01/1998 - "Because topical dioxopromethazine may cause photoallergic contact dermatitis followed by long-lasting photosensitivity even after contact has been discontinued, its withdrawal from the market is recommended." 09/01/1998 - "Dioxopromethazine-induced photoallergic contact dermatitis followed by persistent light reaction." 09/01/1998 - "Although photosensitivity after photoallergy to topical phenothiazine antihistamines is well known, there have been no previous reports of dioxopromethazine inducing this phenomenon. "
3.	Skin Diseases (Skin Disease) 02/02/1970 - "[The introduction of 9,9-dioxopromethazine (Prothanon) into the treatment of skin diseases in hospitalized patients]."
4.	Pruritus (Itching) 09/01/1998 - "A housewife used 0.5% dioxopromethazine in Prothanon gel for palpebral pruritus and developed severe dermatitis of the lower eyelids with spread to the sun-exposed areas. "
5.	Hemorrhoids 02/02/1970 - "[Use of Prothanon suppositories in the treatment of hemorrhoids]."

Related Drugs and Biologics

1.	dioxopromethazine
2.	Suppositories (Vaginal Suppositories)
3.	Histamine Antagonists (Antihistamines)
4.	phenothiazine