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diethyl phthalate

structure

Also Known As:

phthalic acid diethyl ester

Networked: 32 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - diethyl phthalate: 32

Experts

1.	Calafat, Antonia M: 2 articles (01/2018 - 10/2014)
2.	Milic, Natasa: 2 articles (03/2017 - 08/2015)
3.	Cao, Xueying: 1 article (09/2022)
4.	Lu, Yingang: 1 article (09/2022)
5.	Ma, Jun: 1 article (09/2022)
6.	Ren, Wenjie: 1 article (09/2022)
7.	Tan, Changyin: 1 article (09/2022)
8.	Teng, Ying: 1 article (09/2022)
9.	Bakulski, Kelly M: 1 article (01/2022)
10.	Buxton, Miatta: 1 article (01/2022)

Related Diseases

1.	Erythema 01/01/2007 - "Phytantriol at 3% and 10% in diethyl phthalate produced only slight erythema, which cleared by 48 h. "
2.	Body Weight (Weight, Body) 12/01/2005 - "A two-generation reproductive toxicity study was performed to evaluate the effects of diethyl phthalate on parental reproductive performance, including features of the endocrine system and development and growth of offspring at dietary dose levels of 0, 600, 3000 and 15000 ppm. In F0 and F1 parents, no treatment-related adverse effects were observed in clinical findings, body weights, food consumption, reproductive parameters, and gross or histopathological findings in any treated group. " 02/01/2003 - "DPE was diluted in diethyl phthalate (DEP) to administer a total application volume of 2 ml/kg and concentrations of 0.5, 5 and 50% (approximately equal to 10, 100 and 1000 mg DPE/kg body weight). " 08/01/2020 - "Among the phthalates, exposure to diethyl phthalate (DEP) was the highest for the three groups considered (0.0761-0.545 µg/kg body weight/day), followed by bis(2-ethylhxyl)phathalate (DEHP), while the lowest mean intake was found for di-n-octyl phathalate (DNOP; 0.00463-0.0209 µg/kg body weight/day). " 01/01/2009 - "In order to comparatively assess the systemic toxicity and sperm parameters, nine phthalate diesters, including di(2-ethylhexyl) phthalate (DEHP), di(n-butyl) phthalate (DBP), di-n-octyl phthalate (DnOP), diethyl phthalate (DEP), butylbenzyl phthalate (BBP), dimethyl phthalate (DMP), di-isodecyl phthalate (DIDP), diundecyl phthalate (DUP), and di-isononyl phthalate (DINP), and five phthalate monoesters, including mono(2-ethylhexyl) phthalate (MEHP), monobutyl phthalate (MBuP), monobenzyl phthalate (MBeP), monoethyl phthalate (MEP), monomethyl phthalate (MMP), and phthalic acid (PA) were administered orally to Sprague-Dawley male rats at 250 (phthalate monoesters and PA) or 500 mg/kg body weight (bw)/d (phthalate diesters) for 4 wk. Liver weights were significantly increased in g roups treated with DEHP, DBP, BBP, DIDP, DINP, MEHP, and MBuP compared to the control. "
3.	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/01/2015 - "The study objective was to determine if the healthy participants were exposed to diethyl phthalate (DEP) and di (2-ethylhexyl) phthalate (DEHP) and if this exposure could be linked to the development of metabolic syndrome. " 08/01/2015 - "Do diethyl phthalate (DEP) and di-2-ethylhexyl phthalate (DEHP) influence the metabolic syndrome parameters? " 11/01/2023 - "Used primarily in personal care products and excipients for pharmaceuticals, diethyl phthalate (DEP) is a short-chain alkyl phthalate that has been linked to decreased blood pressure, glucose tolerance, and increased gestational weight gain in humans, while in animals it has been associated with atherosclerosis and metabolic syndrome. "
4.	Carcinogenesis 01/01/2020 - "Results from our translational study indicate that low level exposure to diethyl phthalate results in measurable genomic changes in breast tissue with implications in breast carcinogenesis." 01/01/2020 - "Gene expression profiles for low-dose exposure to diethyl phthalate in rodents and humans: a translational study with implications for breast carcinogenesis."
5.	Hepatocellular Carcinoma (Hepatoma) 01/01/2021 - "In the present study, we investigated the roles of four PAEs, butyl benzyl phthalate (BBP), dibutyl phthalate (DBP), dimethyl phthalate (DMP), and diethyl phthalate (DEP), in hepatocellular carcinoma (HCC) cells. "

Related Drugs and Biologics

1.	3,7,11,15- tetramethyl- 1,2,3- hexadecanetriol
2.	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)
3.	phthalic acid (phthalate)
4.	Diethylhexyl Phthalate (DEHP)
5.	Dibutyl Phthalate (Butyl Phthalate)
6.	dimethyl phthalate (dimethylphthalate)
7.	butylbenzyl phthalate (benzyl butyl phthalate)
8.	4-boronic acid benzophenone
9.	phenyl-2-aminoethyl sulfide (PAES)
10.	bis(4-hydroxyphenyl)sulfone

Related Therapies and Procedures

1.	Hearing Aids (Hearing Aid)