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4-chlorobiphenyl

Also Known As:

4-monochlorobiphenyl; 4-chloro-1,1'-biphenyl

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        4-chlorobiphenyl: 6

Experts

1.	Ludewig, Gabriele: 3 articles (11/2010 - 03/2008)
2.	Gregoraszczuk, Ewa L: 2 articles (11/2010 - 03/2008)
3.	Ptak, Anna: 2 articles (11/2010 - 10/2009)
4.	Rak, Agnieszka: 2 articles (11/2010 - 10/2009)
5.	Bochenek, Michał: 1 article (11/2010)
6.	Flor, Susanne: 1 article (11/2010)
7.	Nadolna, Weronika: 1 article (11/2010)
8.	Błachuta, Małgorzata: 1 article (10/2009)
9.	Gregoraszczuk, Ewa Ł: 1 article (10/2009)
10.	Gut, Patrycja: 1 article (10/2009)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 10/28/2009 - "MCF-7 human breast cancer cells were treated for 72h with 4-monochlorobiphenyl (PCB3), 4'-hydroxy-4-monochlorobiphenyl (4-OH-PCB3) or 3'4'-dihydroxy-4-monochlorobiphenyl (3,4-diOH-PCB3) (300nM). " 03/01/2008 - "The aim of this study was to compare the effects of 17β-estradiol (E2) with that of the air pollutant 4-chlorobiphenyl (PCB3) and four of their hydroxylated metabolites on cell cycle, proliferation, and apoptosis in MCF-7 human breast cancer cells at concentrations of 0.1-10nM (E2, 2-OH-E2, and 4-OH-E2) and 0.3-300nM (PCB3, 4-OH-PCB3, and 3, 4-diOH-PCB3) and 24-260h of exposure. " 11/01/2010 - "Induction of cytochrome P450 1A1 in MCF-7 human breast cancer cells by 4-chlorobiphenyl (PCB3) and the effects of its hydroxylated metabolites on cellular apoptosis."
2.	Neoplasms (Cancer) 11/01/2010 - "Inhalation exposure to these compounds, which are readily metabolized to mono- and dihydroxy-biphenyls and further to quinones, is of great concern in light of new studies revealing that at least one such compound, 4-monochlorobiphenyl (PCB3), has tumor initiating and mutagenic activity in rats. "
3.	Shock 09/01/2001 - "Pseudomonas sp. DJ-12 cells were subjected to mild treatments of stress such as exposure to biphenyl, 4-chlorobiphenyl (4CB), 4-hydroxybenzoate (4HBA), ethanol, and heat, and then were examined for production of stress-shock proteins and morphological changes. "
4.	Lymphoma (Lymphomas) 09/15/1976 - "Effect of 4-chlorobiphenyl on substrate transport and phospholipid metabolism in mouse L5178Y lymphoma cells."

Related Drugs and Biologics

1.	Quinones
2.	Air Pollutants (Pollutants, Air)
3.	Proteins (Proteins, Gene)
4.	Phospholipids (Phosphatides)
5.	Cytochrome P-450 Enzyme System (Cytochrome P450)
6.	Ethanol (Ethyl Alcohol)
7.	4-hydroxybenzoic acid (p-hydroxybenzoate)
8.	diphenyl (biphenyl)