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butyl chloride

structure

Also Known As:

1-chlorobutane

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Butanes: 12
        butyl chloride: 5

Experts

1.	Erable, Benjamin: 1 article (08/2005)
2.	Goubet, Isabelle: 1 article (08/2005)
3.	Lamare, Sylvain: 1 article (08/2005)
4.	Legoy, Marie Dominique: 1 article (08/2005)
5.	Maugard, Thierry: 1 article (08/2005)
6.	Seltana, Amira: 1 article (08/2005)
7.	Damborský, J: 1 article (01/2000)
8.	Jesenská, A: 1 article (01/2000)
9.	Sedlácek, I: 1 article (01/2000)

Related Diseases

1.	Carcinogenesis 04/01/1986 - "NTP Toxicology and Carcinogenesis Studies of n-Butyl Chloride (CAS No. 109-69-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)." 04/01/1986 - "Convulsions were observed in male and female rats receiving 250 mg/kg or higher and in 2/10 female mice receiving 1,000 mg/kg. Based on these results, 2-year toxicology and carcinogenesis studies of n-butyl chloride were conducted by administering doses of 0, 60, or 120 mg/kg in corn oil by gavage to groups of 50 male and 50 female rats and doses of 0, 500, or 1,000 mg/kg to groups of 50 male and 50 female mice. " 04/01/1986 - "Toxicology and carcinogenesis studies of n-butyl chloride (greater than 99.5% pure), a solvent as well as an alkylating agent, were conducted by exposing groups of F344/N rats and B6C3F1 mice to n-butyl chloride in corn oil by gavage for 14 days, 13 weeks, and 2 years. "
2.	Uremia 01/01/1981 - "The chemical basis of drug-binding defects in uremia was investigated by studying the effects of extraction of uremic sera with an organic solvent (n-butyl chloride). "
3.	Tuberculosis (Tuberculoses) 01/01/2000 - "tuberculosis H37Rv were found to dehalogenate 1-chlorobutane, 1-chlorodecane, 1-bromobutane, and 1,2-dibromoethane. "
4.	Neoplasms (Cancer) 06/01/1975 - "The administration of comparable doses of ethyl bromide, ethyl iodide, n-butyl chloride, benzyl chloride, and 1-chloromethylnaphthalene to mice resulted in no significant increase in the frequency of lung tumors over that seen in vehicle-treated control mice. " 06/01/1975 - "A slight but significant increase in the average number of lung tumors per mouse was noted following the administration of methyl iodide, n- and i-propyl iodide, sec- and tert-butyl chloride, i-, sec-, and tert-butyl bromide, and n- and sec-butyl iodide. "
5.	Lymphoma (Lymphomas) 04/01/1986 - "n-Butyl chloride was mutagenic in the mouse lymphoma L5178Y/TK± assay in the absence of Aroclor-induced male rat liver S9 and was not tested in the presence of S9. "

Related Drugs and Biologics

1.	Solvents
2.	Corn Oil (Oil, Corn)
3.	Alkylating Agents
4.	butyl bromide
5.	Ethylene Dibromide (1,2 Dibromoethane)
6.	Iodides
7.	Bromides
8.	Aroclors
9.	propyl iodide
10.	1-chloromethylnaphthalene