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dactylarin

isolated from Dactylaria lutea (Deuteromycetes); structure

Also Known As:

3,7-dihydroxy-2',5-dimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2,5)CYCLOHEXADIEN)-4'-ONE

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - dactylarin: 3

Related Diseases

1.	Ascites 10/01/1979 - "Inhibition of energy metabolism in Ehrlich ascites cells treated with dactylarin in vitro." 06/01/1981 - "Interaction of cytotoxic antibiotic dactylarin with glycolytic thiol enzymes in Ehrlich ascites carcinoma cells." 06/01/1981 - "Cytotoxic effect of dactylarin on Ehrlich ascites carcinoma cells is caused by the inhibition of some SH-dependent glycolytic enzymes, especially of hexokinase (EC 2.7.1.1), glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) and 6-phosphofructokinase (EC 2.7.1.11). "
2.	Ehrlich Tumor Carcinoma 08/01/1980 - "Adenosine triphosphate catabolism in Ehrlich ascites tumor cells treated with dactylarin."
3.	Carcinoma (Carcinomatosis) 06/01/1981 - "Interaction of cytotoxic antibiotic dactylarin with glycolytic thiol enzymes in Ehrlich ascites carcinoma cells." 06/01/1981 - "Cytotoxic effect of dactylarin on Ehrlich ascites carcinoma cells is caused by the inhibition of some SH-dependent glycolytic enzymes, especially of hexokinase (EC 2.7.1.1), glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) and 6-phosphofructokinase (EC 2.7.1.11). "

Related Drugs and Biologics

1.	Sulfhydryl Compounds (Thiols)
2.	Phosphofructokinase-1 (Phosphofructokinase 1)
3.	Hexokinase
4.	Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)
5.	Enzymes
6.	Anti-Bacterial Agents (Antibiotics)
7.	Adenosine Triphosphate (ATP)