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taglutimide
bicyclo analog of thalidomide with teratogenic properties; structure
Also Known As:
2-(bicyclo(2.2.1)heptane-2-endo,3-endo-dicarboximido)glutarimide; K-2004; biglumide; 2-(2,6-dioxo-3-piperidinyl)hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Carbocyclic Acids
Phthalic Acids: 1
Phthalimides: 12
Thalidomide: 4688
taglutimide: 2
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Piperidines: 17
Piperidones: 37
Thalidomide: 4688
taglutimide: 2
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Isoindoles: 18
Phthalimides: 12
Thalidomide: 4688
taglutimide: 2
Related Diseases
1.
Stupor
01/01/1980 - "
Pretreatment with taglutimide significantly decreased the plasma dicoumarol level and shortened the duration of hexobarbital-induced narcosis in rats.
"
2.
Seizures (Absence Seizure)
01/01/1979 - "
Taglutimide exhibited no anticonvulsant activity with respect to maximum electroshock or strychnine-induced seizures.
"
3.
Catalepsy
01/01/1979 - "
Only weak potentiation of chlorpromazine-induced catalepsy, but not of reserpine-induced catalepsy was observed after taglutimide pretreatment.
"
Related Drugs and Biologics
1.
Strychnine
2.
Reserpine (Serpasil)
3.
Hexobarbital (Hexenal)
4.
Chlorpromazine (Thorazine)
5.
Dicumarol (Dicoumarol)
6.
Anticonvulsants (Antiepileptic Drugs)