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T-18 (T 18)

structure

Also Known As:

T 18; 4-((2-bromoethyl)(2-bromopropyl)amino)benzenesulfonamide; 4-N-(2-bromoethyl)-4-N-(2-bromopropyl)sulfanilamide

Networked: 81 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kalscheuer, Vera M: 2 articles (08/2008 - 01/2004)
2.	Matsui, Toshimitsu: 2 articles (11/2007 - 12/2003)
3.	Shimoyama, Manabu: 2 articles (11/2007 - 12/2003)
4.	Yamamoto, Katsuya: 2 articles (11/2007 - 12/2003)
5.	Agee, Carl B: 1 article (01/2022)
6.	Beaty, David W: 1 article (01/2022)
7.	Busemann, Henner: 1 article (01/2022)
8.	Carrier, Brandi L: 1 article (01/2022)
9.	Cavalazzi, Barbara: 1 article (01/2022)
10.	Cockell, Charles S: 1 article (01/2022)

Related Diseases

1.	Intellectual Disability (Idiocy) 08/15/2008 - "We have characterized a de novo balanced translocation t(18;20)(q21.1;q11.2) in a female patient with mild to moderate mental retardation (MR) and minor facial anomalies. " 01/01/2006 - "Since the evaluation of MLPA as a screening method, we tested 275 unselected patients with idiopathic mental retardation and detected 12 possible subtelomeric aberrations: a der(11)t(11;20)(qter;qter), a 19pter duplication, a der(18)t(18;10)(qter; pter), a 15qter deletion, a 8pter deletion, a 6qter deletion, a der(X)t(X;1)(pter;qter), a der(X)t(X;3)(pter;pter), a 5qter duplication, a 3pter deletion, and two 3qter duplications. " 11/22/1996 - "In the course of recruiting families with 2 schizophrenic siblings for genome screening and linkage studies, a family was found with mental retardation, schizophrenia, and/or other related psychotic illnesses in individuals who also had an unbalanced or balanced translocation between chromosomes 21-18 [t(18;21)(p11.1;p11.1)]. " 04/30/2005 - "We have compared two such techniques, using bacterial artificial chromosome (BAC) and single nucleotide polymorphism (SNP) arrays in the evaluation of a 45-year-old woman with dysmorphic features, mental retardation, psychosis, and an unbalanced derivative chromosome 18, (46,XX, der(18)t(18;?)(p12;?)). "
2.	Schizophrenia (Dementia Praecox) 07/01/2009 - "Analysis of a t(18;21)(p11.1;p11.1) translocation in a family with schizophrenia." 11/22/1996 - "In the course of recruiting families with 2 schizophrenic siblings for genome screening and linkage studies, a family was found with mental retardation, schizophrenia, and/or other related psychotic illnesses in individuals who also had an unbalanced or balanced translocation between chromosomes 21-18 [t(18;21)(p11.1;p11.1)]. " 07/01/2009 - "Aiming to identify susceptibility gene(s), we investigated a family whose members have either schizophrenia or schizophrenia-spectrum psychosis and carried a t(18;21)(p11.1;p11.1) translocation. " 01/01/2019 - "Materials and Methods: GSE53987 dataset downloaded from GEO-database, which comprised mRNA expression data of post-mortem brain tissue across three regions from control (C) and age-matched subjects (T) of schizophrenia (N = Hippocampus [HIP]: C-15, T-18, Prefrontal cortex [PFC]: C-15, T-19, Associative striatum [STR]: C-18, T-18). "
3.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 09/01/2007 - "Relapsed acute myelogenous leukemia occurring after 18 years with recurrent novel chromosomal abnormality t(18;22)(q23;q11.2)." 09/01/2007 - "A 22-year-old woman presented with lymphadenopathy in a similar manner as she had presented at age 4. At age 4, she was diagnosed with acute myelogenous leukemia (AML) with t(18;22)(q23;q11.2) and received chemotherapy until age 6 under a pediatric study protocol. " 12/01/1999 - "At the time of transplantation, at each stage of myelodysplasia the numbers of patients were 52 with acute myelogenous leukemia (AML), 15 with refractory anemia with excess blasts in transition (RAEB-T), 18 with refractory anemia with excess blasts (RAEB), 11 with refractory anemia (RA), 1 with refractory anemia with ringed sideroblasts (RARS), and 2 with hypoplastic unclassifiable hematologic disorders. "
4.	Sudden Infant Death (SID) 11/01/1981 - "In order to study the respiratory abnormalities during sleep that could select children with a high risk of sudden infant death syndrome (SIDS), 3 groups of children were studied: Group T: 18 control infants; Group G: 22 infants related to children who died from SIDS and group NM: 32 infants with near miss SIDS. "
5.	Lymphadenopathy 09/01/2007 - "A 22-year-old woman presented with lymphadenopathy in a similar manner as she had presented at age 4. At age 4, she was diagnosed with acute myelogenous leukemia (AML) with t(18;22)(q23;q11.2) and received chemotherapy until age 6 under a pediatric study protocol. "

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5.	Solutions
6.	Messenger RNA (mRNA)
7.	Pyridinolcarbamate (P23)
8.	Insulin (Novolin)
9.	Hypoglycemic Agents (Hypoglycemics)
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Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Platelet Transfusion (Blood Platelet Transfusions)
3.	Condoms (Condom)
4.	Transplantation
5.	Tracheotomy