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xylamidine
structure
Also Known As:
N-(2-(3-methoxyphenoxy)propyl)-m-tolylacetamidine tosylate; XYLAMIDINE TOSYLATE ANHYDROUS; xylamidine tosylate
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amidines: 14
xylamidine: 6
Related Diseases
1.
Hypothermia
01/01/1991 - "
In addition, the peripheral 5-HT2 receptor antagonist xylamidine strongly reduced 5-HT-induced hypothermia.
"
01/01/1981 - "
The peripheral 5-HT antagonist, xylamidine, was not an antagonist, suggesting the hypothermia was of central origin.
"
2.
Anorexia
12/01/1989 - "
The peripheral 5-HT-2 antagonist xylamidine had no effect on food intake when administered alone, but antagonised 5-HT-induced anorexia.
"
12/01/1989 - "
Effects of xylamidine on peripheral 5-hydroxytryptamine-induced anorexia.
"
01/01/1989 - "
By contrast, the 5-HT(2) antagonist, ketanserin, and the peripheral 5-HT(2) antagonist, xylamidine, only prevented anorexia due to alpha-Me-5-HT.
"
3.
Hypotension (Low Blood Pressure)
07/10/1992 - "
Each of the 5-HT3 receptor selective antagonists (ICS 205-930 or MDL 72222) produced a dose-dependent attenuation of the Bezold-Jarisch reflex-mediated hypotension and bradycardia, and each of the 5-HT2 receptor selective antagonists (xylamidine, ketanserin or LY 53857) produced a dose-dependent attenuation of the pressor response.
"
4.
Hyperglycemia
04/04/1997 - "
In addition, the peripheral 5-HT2 receptor antagonist, xylamidine, reduced 5-methoxytryptamine-induced hyperglycemia.
"
5.
Bradycardia
07/10/1992 - "
Each of the 5-HT3 receptor selective antagonists (ICS 205-930 or MDL 72222) produced a dose-dependent attenuation of the Bezold-Jarisch reflex-mediated hypotension and bradycardia, and each of the 5-HT2 receptor selective antagonists (xylamidine, ketanserin or LY 53857) produced a dose-dependent attenuation of the pressor response.
"
Related Drugs and Biologics
1.
Ketanserin
2.
5-HT3 Serotonin Receptors (5 HT3 Receptor)
3.
Serotonin Antagonists
4.
Tropisetron (Navoban)
5.
bemesetron
6.
LY 53857