tertatolol (Artex)

RN given refers to parent cpd; structure given in first source

Also Known As:

Artex; Artexal; DL-8-(2'-hydroxy-3'-t-butylaminopropyloxy)thiochroman.HCl; S 2395; S-2395; SE 2395; SE-2395; tertatolol hydrochloride; tertatolol hydrochloride, (+-)-isomer; tertatolol, (+-)-isomer; 2-propanol, 1-((3,40dihydro-2H-1-benzothiopyran-8-yl)oxy)-3-((1,1-dimethylethyl)amino)-

Networked: 42 relevant articles (4 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bernaud, Corine: 1 article (10/2003)
2.	Chanard, Jacques: 1 article (10/2003)
3.	Hurault de Ligny, Bruno: 1 article (10/2003)
4.	Lavaud, Sylvie: 1 article (10/2003)
5.	Moulin, Bruno: 1 article (10/2003)
6.	Toupance, Olivier: 1 article (10/2003)
7.	Larrarte, E: 1 article (06/2001)
8.	Margareto, J: 1 article (06/2001)
9.	Marti, A: 1 article (06/2001)
10.	Martinez, J A: 1 article (06/2001)

Related Diseases

1.	Hypertension (High Blood Pressure) 11/01/1989 - "Renal perfusion has been shown to be preserved or improved during treatment by tertatolol in patients with arterial hypertension. " 12/01/1989 - "Additional benefits of combining beta-blockade and renal vasodilation in the treatment of mild to moderate hypertension: Tertatolol International Multicentre Study results." 01/01/1993 - "Beta-Blockers in the Treatment of Hypertension in the 90's: Experience with Tertatolol. " 07/01/1990 - "[Renal effects of intravenous tertatolol in essential arterial hypertension]." 11/01/1989 - "Tertatolol has been studied in 2,338 patients with mild to moderate hypertension over a one year period. "
2.	Chronic Kidney Failure (Chronic Renal Failure) 07/01/1988 - "Tertatolol ameliorates renal function in rats with chronic renal failure." 01/01/1991 - "These results indicate that tertatolol possesses novel renal haemodynamic properties in hypertensive patients with chronic renal failure. " 01/01/1991 - "To assess the potential benefit of drug-induced renal haemodynamic changes in patients with chronic renal failure, we have evaluated the effects of the beta-blocking agent tertatolol on blood pressure, glomerular filtration rate, and renal plasma flow. " 01/01/1991 - "Chronic effects of tertatolol on renal function in hypertensive patients with mild chronic renal failure." 11/01/1989 - "Tertatolol in chronic renal failure. "
3.	Migraine Disorders (Migraine) 09/10/1992 - "It is therefore suggested that tertatolol may prove effective in the treatment of migraine." 09/10/1992 - "Two other beta-adrenoceptor antagonists, one (propranolol) with and one (pindolol) without antimigraine actions, were compared (doses: 0.03, 0.1, 0.3 and 1 mg/kg i.v.) with tertatolol in this animal experimental model of migraine. " 09/10/1992 - "Effects of tertatolol, a beta-adrenoceptor antagonist with agonist affinity at 5-HT1A receptors, in an animal model of migraine: comparison with propranolol and pindolol."
4.	Hypertrophy 10/01/1989 - "In 15 previously untreated hypertensive subjects with left ventricular (LV) hypertrophy who responded favorably (supine blood pressure less than or equal to 140/90 mm Hg) to antihypertensive treatment with a nonselective beta-blocking agent, tertatolol, the effects of reversal of LV hypertrophy on systolic and diastolic function were assessed. "
5.	Essential Hypertension 01/01/1986 - "Renal hemodynamic effects of tertatolol in essential hypertension." 01/01/1993 - "In a first study [Paillard et al., 1986], tertatolol (T) 5 mg and propranolol (Pr) 160 mg (SR) were given orally for 15 days to 2 groups of 9 patients with essential hypertension. " 07/01/1990 - "The acute renal effects of intravenous tertatolol were studied in eight patients with moderate essential hypertension: the study included a 100 mmol/day sodium intake during 3 days. " 01/01/1993 - "Comparative renal and cardiac effects of tertatolol and enalapril in essential hypertension." 07/01/1988 - "These results show that both tertatolol and nadolol redistribute cardiac output to the kidneys in patients with essential hypertension."

Related Drugs and Biologics

1.	Antihypertensive Agents (Antihypertensives)
2.	Propranolol (Inderal)
3.	Adrenergic beta-Antagonists (beta-Adrenergic Blocking Agents)
4.	Lipids
5.	Amlodipine (Norvasc)
6.	Sodium
7.	Calcium Channel Blockers (Blockers, Calcium Channel)
8.	Adrenergic Receptors (Adrenergic Receptor)
9.	Inulin
10.	Adrenergic Agents (Adrenergic Drugs)

Related Therapies and Procedures

1.	Vagotomy