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pteroic acid

structure

Also Known As:

4-((2-amino-4-hydroxy-6-pteridylmethyl)amino)benzoic acid; p-((2-amino-4-hydroxy-6-pteridylmethyl)amino)benzoic acid

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        pteroic acid: 5
Biological Factors: 2472
- Biological Pigments: 1
  - Pterins: 160
    - pteroic acid: 5

Experts

1.	Kühle, Berit: 1 article (01/2013)
2.	Müller, Cristina: 1 article (01/2013)
3.	Ross, Tobias L: 1 article (01/2013)
4.	Green, Mark A: 1 article (05/2005)
5.	Ke, Chun-Yen: 1 article (05/2005)
6.	Mathias, Carla J: 1 article (05/2005)
7.	Borch, R F: 1 article (01/2001)
8.	Steinberg, G: 1 article (01/2001)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2013 - "A novel (68)Ga-labeled pteroic acid-based pet tracer for tumor imaging via the folate receptor." 05/25/2005 - "Targeting the tumor-associated folate receptor with an 111In-DTPA conjugate of pteroic acid." 05/25/2005 - "In control studies, tumor targeting with this pteroic acid conjugate appears as effective as that seen using (111)In-DTPA-folate, a radiopharmaceutical that has progressed to clinical trials for detection of folate receptor-expressing gynecological tumors." 01/04/2001 - "A novel nitroheterocyclic bis(haloethyl)phosphoramidate prodrug linked through lysine to a pteroic acid has been prepared and evaluated as a potential alkylating agent to target tumor cells that overexpress the folate receptor. "
2.	Weight Gain 01/01/1986 - "Fingerling catfish raised under controlled conditions on feed containing 130 mg/kg of pteroic acid failed to gain weight and developed anemia with the characteristic red cell morphologic features that are seen in the naturally occurring disease. "
3.	Psittacosis (Ornithosis) 09/01/1948 - "The effects of certain analogues of pteroylglutamic acid and of pteroic acid on the growth of psittacosis virus and its inhibition by sulfadiazine are reported. "
4.	Anemia 01/01/1986 - "Fingerling catfish raised under controlled conditions on feed containing 130 mg/kg of pteroic acid failed to gain weight and developed anemia with the characteristic red cell morphologic features that are seen in the naturally occurring disease. " 01/01/1986 - "We conclude that severe anemia in channel catfish can be caused by abnormal folate metabolism and may be due to ingestion of folic acid-breakdown products, such as pteroic acid. "

Related Drugs and Biologics

1.	Folic Acid (Vitamin M)
2.	Radiopharmaceuticals
3.	Sulfadiazine (Sulphadiazine)
4.	Prodrugs
5.	Lysine (L-Lysine)
6.	Alkylating Agents
7.	phosphoramidic acid