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captax

RN given refers to parent cpd

Also Known As:

2-mercaptobenzothiazole; 2-thiobenzothiazole; captax, bismuth(+3) salt; captax, cobalt(+2) salt; captax, copper(+2) salt; captax, lead(+2) salt; captax, mercury (+2) salt; captax, potassium salt; captax, silver(+1) salt; captax, sodium salt; captax, zinc salt; mebetizol

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Drug Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Thiazoles: 23
      - Benzothiazoles: 24
        captax: 9
- 2-Ring Heterocyclic Compounds
  - Benzothiazoles: 24
    - captax: 9

Experts

1.	Siegel, Paul D: 2 articles (01/2008 - 08/2007)
2.	Simoyi, Reuben H: 2 articles (01/2008 - 08/2007)
3.	Chipinda, Itai: 2 articles (01/2008 - 08/2007)
4.	Sorahan, T: 1 article (04/2009)
5.	Zhang, Xing-Dong: 1 article (01/2008)
6.	Hettick, Justin M: 1 article (08/2007)
7.	Tsuchiya, Toshie: 1 article (11/2005)
8.	Matsuoka, Atsuko: 1 article (11/2005)
9.	Isama, Kazuo: 1 article (11/2005)
10.	Bledsoe, T A: 1 article (08/2005)

Related Diseases

1.	Allergic Contact Dermatitis 01/01/2008 - "The rubber accelerator, 2-mercaptobenzothiazole (MBT), is known to cause allergic contact dermatitis (ACD), but the mechanism is unknown. " 08/01/2007 - "The rubber accelerator, 2-mercaptobenzothiazole (MBT), has been reported to cause allergic contact dermatitis from gloves and other rubber products, but its chemical fate when exposed to occupational oxidants and the mechanism of its pathogenesis are not known. " 08/01/2005 - "2-Mercaptobenzothiazole and zinc dialkyldithiocarbamates are commonly used sulfur-containing rubber vulcanization accelerators known to cause allergic contact dermatitis. " 02/01/1994 - "We studied 3 contact sensitizers present in rubber products, ethylbutyl thiourea (EBT), 2-mercaptobenzothiazole (MBT) and 2,2-dithio-bis-benzothiazole (MBTS), to relate the amount of sensitizer eliciting allergic contact dermatitis to the quantity leaching from a product into various biological fluids: normal saline, human plasma and 3 synthetic sweat solutions of pH 5.5 to 7.5. "
2.	Neoplasms (Cancer) 04/01/2009 - "To investigate cancer risks in chemical production workers exposed to 2-mercaptobenzothiazole (MBT). " 04/01/2009 - "Cancer risks in chemical production workers exposed to 2-mercaptobenzothiazole." 10/01/1993 - "Mortality trends for 1059 production workers at a rubber chemicals plant in Nitro, West Virginia were examined to find whether they had increased mortality from cancer associated with exposure to 2-mercaptobenzothiazole (MBT). "
3.	Polyploidy 11/01/2005 - "In vitro induction of polyploidy and chromatid exchanges by culture medium extracts of natural rubbers compounded with 2-mercaptobenzothiazole as a positive control candidate for genotoxicity tests."
4.	Dermatomycoses (Dermatophytosis) 06/01/1995 - "APB inhibited the growth of 3 Trichophyton strains at 65 micrograms/ml. 2-Mercaptobenzothiazole was not effective at 125 micrograms/ml and ketoconazole inhibited the growth at 20-30 micrograms/ml. Treatment of experimental dermatophytosis in guinea pigs using 2.5% APB cream was studied in comparison to Canesten cream (1% clotrimazole). "
5.	Dermatitis 01/01/1981 - "Dermatitis from 2-mercaptobenzothiazole in photographic films."

Related Drugs and Biologics

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6.	Clotrimazole (Lotrimin)
7.	dibenzothiazyl disulfide
8.	ethylbutyl thiourea
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