phosphorylethanolamine (phosphoethanolamine)

RN given refers to parent cpd; structure

Also Known As:

phosphoethanolamine; ethanolamine phosphate; calcium 2-aminoethanol phosphate; phosphorylethanolamine Ca (1:1) salt; phosphorylethanolamine magnesium (1:1) salt; phosphorylethanolamine zinc salt; phosphorylethanolamine, 3H-labeled cpd; phosphorylethanolamine, cobalt (2+) (1:1) salt

Networked: 276 relevant articles (7 outcomes, 29 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - phosphorylethanolamine: 276
- Alcohols: 595
  - Ethanol: 23169
    - Ethanolamines: 16
      - phosphorylethanolamine: 276
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - phosphorylethanolamine: 276

Experts

1.	O'Regan, M H: 6 articles (09/2003 - 01/2000)
2.	Phillis, J W: 6 articles (09/2003 - 01/2000)
3.	Chierice, Gilberto Orivaldo: 5 articles (11/2018 - 01/2012)
4.	Maria, Durvanei Augusto: 5 articles (11/2018 - 01/2012)
5.	Klomp, Dennis W J: 4 articles (01/2019 - 12/2011)
6.	Wijnen, Jannie P: 4 articles (01/2019 - 08/2012)
7.	Meneguelo, Renato: 4 articles (07/2018 - 01/2012)
8.	Choi, Jae-Yeon: 4 articles (03/2015 - 04/2005)
9.	Voelker, Dennis R: 4 articles (03/2015 - 04/2005)
10.	Ferreira, Adilson Kleber: 4 articles (07/2013 - 01/2012)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2017 - "In the internet era, information can be broadcasted widely, and this happened with phosphoethanolamine in Brazil, where this substance was claimed by the population to be the "cure for cancer." This is a cross-sectional study developed by the Brazilian Society of Clinical Oncology (SBOC). " 01/01/2018 - "Elevated phosphoethanolamine (PE) is frequently observed in MRS studies of human cancers and xenografts. " 05/01/2017 - "Notwithstanding its approval by the National Committee for Ethics in Research (Conep) on April 19, 2016, a trial of the so-called "synthetic" phosphoethanolamine (syn-phospho) pill in cancer patients raises ethical concerns. " 01/01/2017 - "Most oncologists in Brazil do not believe that synthetic phosphoethanolamine is active in cancer treatment, do not recommend its use without proper evaluation, and state that it should only be available to patients in the context of clinical trials." 01/01/2017 - "A "miracle" cancer drug in the era of social media: A survey of Brazilian oncologists' opinions and experience with phosphoethanolamine."
2.	Parkinson Disease (Parkinson's Disease) 07/01/1986 - "We measured the concentration of gamma-aminobutyric acid (GABA), glutamic acid, and o-phosphoethanolamine in autopsied brain of 9 patients who died with idiopathic Parkinson's disease and 10 control subjects. " 01/01/1988 - "Results showed statistically significant decreases in the levels of gamma-aminobutyric acid, homocarnosine, phosphoethanolamine, and threonine, and elevation of ornithine levels, in the CSF of de novo patients with Parkinson's disease compared with controls. " 01/01/2001 - "Nigral activity of the catabolic enzyme phospholipase A2 was normal in the Parkinson's disease group, whereas that of the biosynthetic enzymes phosphoethanolamine cytidylyltransferase, phosphocholine cytidylyltransferase, and phosphatidylserine synthase were elevated 193, 48 and 38%, respectively, possibly representing a compensatory response to repair membrane phospholipids. "
3.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/01/2011 - "Role of ethanolamine phosphate in the hippocampus of rats with acute experimental autoimmune encephalomyelitis." 02/01/2020 - "Oxidative Stress and Lymphocyte Alterations in Chronic Relapsing Experimental Allergic Encephalomyelitis in the Rat Hippocampus and Protective Effects of an Ethanolamine Phosphate Salt." 01/01/2011 - "Here, we assessed the effects of acute experimental autoimmune encephalomyelitis (EAE) on the rat hippocampal somatostatinergic system and whether administration of an ethanolamine phosphate salt could prevent the appearance of the clinical signs and the impairment of the somatostatinergic system in this pathological condition. "
4.	Bacterial Infections (Bacterial Infection) 01/01/2023 - "However, the rapid spread of the transferable gene, mcr-1 which confers colistin resistance by encoding a phosphoethanolamine transferase that modifies lipid A of the bacterial membrane, threatens the efficacy of colistin for the treatment of drug-resistant bacterial infections. " 12/13/2016 - "MCR-1 is a phosphoethanolamine (pEtN) transferase that modifies the pEtN moiety of lipid A, conferring resistance to colistin, which is an antibiotic belonging to the class of polypeptide antibiotics known as polymyxins and is the last-line antibiotic used to treat multidrug resistant bacterial infections. "
5.	Hypophosphatasia 12/01/1959 - "A genetical study of ethanolamine phosphate excretion in hypophosphatasia." 06/01/2013 - "Very low ALP level (27 IU/ml) suggested the diagnosis of hypophosphatasia, which was supported by an elevated urine phosphoethanolamine/Cr of 84 μmol/mmol (reference range, <25 μmol/mmol) and serum pyridoxal-5'-phosphate of 393 μg/L (reference range, 3.6-18 μg/L). " 12/01/2012 - "Phosphoethanolamine normal range in pediatric urines for hypophosphatasia screening." 01/01/1994 - "Urinary phosphoethanolamine, a typical marker of hypophosphatasia, was absent from all specimens, which rules out the possible diagnosis of such disorder in these patients. " 06/01/1980 - "[Hypophosphatasia with normal urinary phosphoethanolamine in a 22-month-old girl]."

Related Drugs and Biologics

1.	Salts
2.	polyethylene glycol 2000
3.	Ethylene Glycol (Monoethylene Glycol)
4.	Cholesterol
5.	gamma-Aminobutyric Acid (GABA)
6.	Phosphatidylcholines (Phosphatidylcholine)
7.	Taurine
8.	Glycine (Aminoacetic Acid)
9.	Glutamine (L-Glutamine)
10.	Lipid A

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Time-to-Treatment
4.	Enzyme Replacement Therapy
5.	Quantum Dots (Quantum Dot)