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oxybutynin (Tavor)

RN given refers to parent cpd

Also Known As:

Tavor; Ryol; Ditropan; Oxytrol; 4-(diethylamino)-2-butynyl-alpha-cyclohexyl-alpha-hydroxybenzeneacetate; 4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate; AbZ brand of oxybutynin hydrochloride; Abbott brand of oxybutynin hydrochloride; Aliud brand of oxybutynin hydrochloride; Allphar brand of oxybutynin hydrochloride; Alpharma brand of oxybutynin hydrochloride; Apo-Oxybutynin; Apotex brand of oxybutynin hydrochloride; Asofarma brand of oxybutynin hydrochloride; Aventis brand of oxybutynin hydrochloride; Azupharma brand of oxybutynin hydrochloride; Berk brand of oxybutynin hydrochloride; Byk brand of oxybutynin hydrochloride; CCD brand of oxybutynin hydrochloride; Clonmel brand of oxybutynin hydrochloride; Contimin; Cystonorm; Cystrin; Dresplan; Dridase; Driptane; Fournier brand of oxybutynin hydrochloride; Gen-Oxybutynin; Genpharm brand of oxybutynin hydrochloride; Heumann brand of oxybutynin hydrochloride; Hoyer brand of oxybutynin hydrochloride; Janssen brand of oxybutynin hydrochloride; Kade brand of oxybutynin hydrochloride; Novo-Oxybutynin; Novopharm brand of oxybutynin hydrochloride; Nu-Oxybutyn; Nu-Pharm brand of oxybutynin hydrochloride; Ortho brand of oxybutynin hydrochloride; Oxyb AbZ; Oxybugamma; Oxybutin Holsten; Oxybuton; Oxybutynin AL; Oxybutynin AZU; Oxybutynin Heumann; Oxybutynin Hexal; Oxybutynin Stada; Oxybutynin-Puren; Oxybutynin-ratiopharm; Oxymedin; PMS-Oxybutynin; Pfleger brand of oxybutynin hydrochloride; Pharmascience brand of oxybutynin hydrochloride; Pollakisu; Renamel; Sanofi Synthelabo brand of oxybutynin hydrochloride; Seid brand of oxybutynin hydrochloride; Spasmex Oxybutynin; Spasyt; Stadapharm brand of oxybutynin hydrochloride; TAD brand of oxybutynin hydrochloride; Wörwag brand of oxybutynin hydrochloride; Zatur; ct-Arzneimittel brand of oxybutynin hydrochloride; esparma brand of oxybutynin hydrochloride; gelnique; oxybutynin chloride; oxybutynin hydrochloride; oxybutynin von ct; ratiopharm brand of oxybutynin hydrochloride

Networked: 499 relevant articles (98 outcomes, 122 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 58
- Carboxylic Acids: 83
  - Hydroxy Acids: 24
    - Mandelic Acids
      - oxybutynin: 499
  - Carbocyclic Acids
    - Mandelic Acids
      - oxybutynin: 499

Experts

1.	Kauffman, Paulo: 17 articles (09/2015 - 05/2011)
2.	Wolosker, Nelson: 17 articles (09/2015 - 05/2011)
3.	Puech-Leão, Pedro: 16 articles (09/2015 - 05/2011)
4.	Sand, Peter K: 15 articles (01/2015 - 06/2003)
5.	Dmochowski, Roger R: 15 articles (06/2012 - 08/2002)
6.	Krutman, Mariana: 12 articles (09/2015 - 10/2012)
7.	Davila, G Willy: 9 articles (02/2012 - 08/2002)
8.	Teivelis, Marcelo Passos: 6 articles (12/2014 - 01/2014)
9.	Yamada, Shizuo: 6 articles (09/2012 - 11/2004)
10.	Appell, Rodney A: 6 articles (03/2006 - 01/2002)

Related Diseases

1.	Overactive Urinary Bladder (Overactive Bladder) 07/01/2015 - "Intravesical oxybutynin is highly effective in the treatment of overactive bladder. " 01/01/2002 - "While oxybutynin IR has proven effective for the treatment of overactive bladder, its extended use can be limited by adverse effects, particularly dry mouth. " 03/01/1995 - "In summary, oxybutynin is one of the few drugs proven to be beneficial in some patients with overactive detrusor function. " 01/01/2011 - "In a recent placebo-controlled Phase III study, oxybutynin chloride topical gel (OTG) significantly improved urinary continence in patients with overactive bladder. " 01/01/2009 - "*In two well designed trials in patients with overactive bladder, transdermal oxybutynin 3.9 mg/day decreased the number of incontinence episodes and increased average voided volume to a significantly greater extent than placebo. "
2.	Hyperhidrosis 09/01/2014 - "Oxybutynin is effective for treating bothersome hyperhidrosis, even at atypical locations and most patients cope well with the side effects." 01/01/2008 - "Oxybutynin has been proven to be effective in patients with generalized hyperhidrosis. " 12/01/2014 - "Among patients with good initial responses to oxybutynin, more than 90 % experienced moderate or great improvement in their palmar sweating, as well as in their hyperhidrosis in other sites, after 6 months. " 09/01/2014 - "Oxybutynin has provided good results and is an alternative for treating hyperhidrosis at common sites. " 05/01/2013 - "Treatment of plantar hyperhidrosis with oxybutynin presents good results and improves quality of life. "
3.	Urge Urinary Incontinence (Urge Incontinence) 01/01/2005 - "Although most novel anticholinergic medications are effective and well tolerated in children, in our experience oxybutynin extended release provides superior relief for urge urinary incontinence in children. " 06/01/1990 - "We found oxybutynin chloride significantly more effective than placebo at reducing the symptoms of urgency and urge incontinence and more effective at reducing the height of the highest unstable detrusor contraction. " 12/01/2003 - "Although oral oxybutynin has been effective in controlling urinary urge incontinence and in decreasing incontinence episodes, adverse events, particularly dry mouth, often cause patients to discontinue oral therapy and to endure incontinence. " 10/01/2005 - "Data were combined from 3 flexible dosing studies of a total of 420 patients with urge urinary incontinence or mixed incontinence in whom ER oxybutynin dose adjustments were made to achieve the optimal balance between efficacy and tolerability, as judged by each participant. " 10/01/2005 - "Efficacy and safety of extended release oxybutynin for the treatment of urge incontinence: an analysis of data from 3 flexible dosing studies."
4.	Nocturnal Enuresis (Bedwetting) 09/01/1992 - "In children, the drug is prescribed most frequently (56%) for conditions outside the licensed indications, particularly nocturnal enuresis, a condition for which the efficacy of Ditropan has not been established. " 05/01/2011 - "Oxybutynin is an anticholinergic drug that has not been proven to be effective for treatment of nocturnal enuresis not accompanied by daytime symptoms, such as urgency. " 05/01/2011 - "Is oxybutynin a safe and effective drug for treating nocturnal enuresis? " 05/01/2011 - "Oxybutynin for treatment of nocturnal enuresis in children." 11/01/2007 - "In the treatment of children with monosymptomatic nocturnal enuresis maximum voided volume can be increased significantly through holding exercises, but not with oxybutynin chloride alone. "
5.	Neurogenic Urinary Bladder (Bladder, Neurogenic) 11/01/2006 - "Oxybutynin is extremely safe and effective in almost every population including children, the elderly, and those who have neurogenic bladder. " 01/01/2004 - "A few noncomparative studies have shown promising results with oxybutynin ER in the treatment of adult and paediatric patients with neurogenic bladder dysfunction secondary to neuronal injury. " 03/01/1988 - "The present long-term trial proved that oxybutynin hydrochloride is an exceedingly effective and safe agent for clinical management of unstable bladder and overactive neurogenic bladder." 01/01/2005 - "All 3 formulations of oxybutynin are safe and effective in children with neurogenic bladder dysfunction." 07/01/1990 - "The clinical efficacy of oxybutynin hydrochloride was studied on 21 patients with neurogenic bladder or unstable bladder complaining of urinary frequency, urgency and urgent incontinence. "

Related Drugs and Biologics

1.	tolterodine (Detrol)
2.	oxybutynin (Tavor)
3.	Deamino Arginine Vasopressin (Desmopressin)
4.	propiverine
5.	quinuclidin- 3'- yl- 1- phenyl- 1,2,3,4- tetrahydroisoquinoline- 2- carboxylate monosuccinate (solifenacin)
6.	Cholinergic Antagonists (Anticholinergics)
7.	Imipramine (Janimine)
8.	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)
9.	tyramine-deoxysorbitol
10.	darifenacin

Related Therapies and Procedures

1.	Intravesical Administration
2.	Home Nursing (Nursing, Home)
3.	Female Contraceptive Devices (Vaginal Ring)
4.	Intermittent Urethral Catheterization
5.	Oral Administration