oxybutynin (Tavor)

RN given refers to parent cpd

Also Known As:

Tavor; Ryol; Ditropan; Oxytrol; 4-(diethylamino)-2-butynyl-alpha-cyclohexyl-alpha-hydroxybenzeneacetate; 4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate; Apo-Oxybutynin; Contimin; Cystonorm; Cystrin; Dresplan; Dridase; Driptane; Gen-Oxybutynin; Novo-Oxybutynin; Nu-Oxybutyn; Oxyb AbZ; Oxybugamma; Oxybutin Holsten; Oxybuton; Oxybutynin AL; Oxybutynin AZU; Oxybutynin Heumann; Oxybutynin Hexal; Oxybutynin Stada; Oxybutynin-Puren; Oxybutynin-ratiopharm; Oxymedin; PMS-Oxybutynin; Pollakisu; Renamel; Spasmex Oxybutynin; Spasyt; Zatur; gelnique; oxybutynin chloride; oxybutynin hydrochloride; oxybutynin von ct

Networked: 694 relevant articles (143 outcomes, 180 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 140
- Carboxylic Acids: 986
  - Hydroxy Acids: 97
    - Mandelic Acids
      - oxybutynin: 694
  - Carbocyclic Acids
    - Mandelic Acids
      - oxybutynin: 694

Experts

1.	Wolosker, Nelson: 21 articles (01/2021 - 05/2011)
2.	Kauffman, Paulo: 20 articles (06/2020 - 05/2011)
3.	Puech-Leão, Pedro: 19 articles (01/2021 - 05/2011)
4.	Dmochowski, Roger R: 16 articles (04/2016 - 08/2002)
5.	Sand, Peter K: 15 articles (01/2015 - 06/2003)
6.	Krutman, Mariana: 12 articles (09/2015 - 10/2012)
7.	Davila, G Willy: 9 articles (02/2012 - 08/2002)
8.	Teivelis, Marcelo Passos: 8 articles (02/2018 - 01/2014)
9.	Yamada, Shizuo: 8 articles (09/2012 - 11/2004)
10.	Del Boz, Javier: 6 articles (01/2021 - 05/2016)

Related Diseases

1.	Overactive Urinary Bladder (Overactive Bladder) 07/01/2015 - "Intravesical oxybutynin is highly effective in the treatment of overactive bladder. " 01/01/2002 - "While oxybutynin IR has proven effective for the treatment of overactive bladder, its extended use can be limited by adverse effects, particularly dry mouth. " 03/01/1995 - "In summary, oxybutynin is one of the few drugs proven to be beneficial in some patients with overactive detrusor function. " 01/01/2011 - "In a recent placebo-controlled Phase III study, oxybutynin chloride topical gel (OTG) significantly improved urinary continence in patients with overactive bladder. " 01/01/2009 - "*In two well designed trials in patients with overactive bladder, transdermal oxybutynin 3.9 mg/day decreased the number of incontinence episodes and increased average voided volume to a significantly greater extent than placebo. "
2.	Hyperhidrosis 09/01/2014 - "Oxybutynin is effective for treating bothersome hyperhidrosis, even at atypical locations and most patients cope well with the side effects." 01/01/2008 - "Oxybutynin has been proven to be effective in patients with generalized hyperhidrosis. " 11/01/2020 - "This real life study suggests that oxybutynin is effective and safe for treatment of hyperhidrosis, both in children and adults, with mild and tolerable side effects, with significant improvement in HDSS." 05/01/2022 - "Treatment of primary palmar hyperhidrosis with oxybutynin is a good initial alternative for treatment given that it gives better results and much more improvement in QOL when compared to topical ACH. " 02/01/2018 - "There was a significant improvement in quality of life and a reduction in sweating and malodor after six weeks of treatment with topical agents and oxybutynin in patients with both hyperhidrosis and osmidrosis. "
3.	Urge Urinary Incontinence (Urge Incontinence) 06/01/1990 - "We found oxybutynin chloride significantly more effective than placebo at reducing the symptoms of urgency and urge incontinence and more effective at reducing the height of the highest unstable detrusor contraction. " 10/01/2005 - "Data were combined from 3 flexible dosing studies of a total of 420 patients with urge urinary incontinence or mixed incontinence in whom ER oxybutynin dose adjustments were made to achieve the optimal balance between efficacy and tolerability, as judged by each participant. " 10/01/2005 - "Efficacy and safety of extended release oxybutynin for the treatment of urge incontinence: an analysis of data from 3 flexible dosing studies." 03/01/2003 - "All had urge incontinence and were enrolled in a placebo controlled oxybutynin trial. " 02/01/2000 - "In short (< or =6 weeks) randomised, double-blind clinical trials of patients with detrusor instability, extended-release oxybutynin 5 to 30mg once daily significantly reduced the mean weekly number of urge incontinence episodes by 84 to 90%. "
4.	Urinary Incontinence 10/01/2005 - "Individualized dosing with ER oxybutynin was associated with highly effective and well tolerated control of urinary incontinence with more than 40% of patients achieving total dryness." 01/01/2024 - "Oxybutynin, an agent for treating urinary incontinence, is recently claimed with protective effects on bladder ultrastructure. " 01/01/2015 - "Efficacy and safety of oxybutynin topical gel 3% in patients with urgency and/or mixed urinary incontinence: a randomized, double-blind, placebo-controlled study." 01/01/2007 - "Safety and tolerability of extended-release oxybutynin once daily in urinary incontinence: combined results from two phase 4 controlled clinical trials." 01/01/2020 - "It is uncertain whether surgery compared with oxybutynin leads to more women being dry (83% vs 0%; OR 195.89, 95% confidence interval (CI) 9.91 to 3871.03) or having less urgency urinary incontinence (13% vs 43%; RR 0.29, 95% CI 0.09 to 0.94) because the quality of this evidence is very low. "
5.	Nocturnal Enuresis (Bedwetting) 09/01/1992 - "In children, the drug is prescribed most frequently (56%) for conditions outside the licensed indications, particularly nocturnal enuresis, a condition for which the efficacy of Ditropan has not been established. " 05/01/2011 - "Is oxybutynin a safe and effective drug for treating nocturnal enuresis? " 06/27/2019 - "To compare the results of the standard urotherapy alone and associated with pelvic floor muscle training alone, and in combination with oxybutynin in treatment of nonmonosymptomatic nocturnal enuresis. " 05/01/2011 - "Oxybutynin for treatment of nocturnal enuresis in children." 11/01/2007 - "In the treatment of children with monosymptomatic nocturnal enuresis maximum voided volume can be increased significantly through holding exercises, but not with oxybutynin chloride alone. "

Related Drugs and Biologics

1.	Tolterodine Tartrate (Detrol)
2.	Cholinergic Antagonists (Anticholinergics)
3.	Deamino Arginine Vasopressin (Desmopressin)
4.	oxybutynin (Tavor)
5.	Muscarinic Antagonists
6.	Atomoxetine Hydrochloride (Strattera)
7.	Solifenacin Succinate
8.	propiverine
9.	tyramine-deoxysorbitol
10.	Tamsulosin (Flomax)

Related Therapies and Procedures

1.	Therapeutics
2.	Intravesical Administration
3.	Stents
4.	Home Nursing (Nursing, Home)
5.	Transcutaneous Electric Nerve Stimulation (TENS)