orotidylic acid

structure

Also Known As:

5-(dihydrogen phosphate)orotidine; orotidine 5'-monophosphate

Networked: 10 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleotides: 48
      - Uracil Nucleotides: 40
        Uridine Monophosphate: 182
        orotidylic acid: 10
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Ribonucleotides: 307
    - Uracil Nucleotides: 40
      - Uridine Monophosphate: 182
        orotidylic acid: 10
  - Pyrimidine Nucleotides: 48
    - Uracil Nucleotides: 40
      - Uridine Monophosphate: 182
        orotidylic acid: 10

Experts

1.	Krungkrai, Jerapan: 5 articles (06/2016 - 06/2004)
2.	Krungkrai, Sudaratana R: 5 articles (06/2016 - 06/2004)
3.	Horii, Toshihiro: 3 articles (06/2006 - 06/2004)
4.	Prapunwattana, Phisit: 2 articles (02/2005 - 06/2004)
5.	Imprasittichail, Waranya: 1 article (03/2014)
6.	Krungkrail, Jerapan: 1 article (03/2014)
7.	Roytrakul, Sittiruk: 1 article (03/2014)
8.	Kanchanaphum, Panan: 1 article (12/2009)
9.	Adachi, Hiroaki: 1 article (06/2006)
10.	Inoue, Tsuyoshi: 1 article (06/2006)

Related Diseases

1.	Malaria 06/01/2006 - "Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum." 06/11/2004 - "Orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum." 03/01/2014 - "A unique insertion of low complexity amino acid sequence underlies protein-protein interaction in human malaria parasite orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase." 12/11/2009 - "We have previously shown that orotate phosphoribosyltransferase (OPRT) and orotidine 5'-monophosphate decarboxylase (OMPDC) in human malaria parasite Plasmodium falciparum form an enzyme complex, containing two subunits each of OPRT and OMPDC. " 12/11/2009 - "Kinetic benefits and thermal stability of orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase enzyme complex in human malaria parasite Plasmodium falciparum."
2.	Hepatocellular Carcinoma (Hepatoma) 05/01/1973 - "Orotate phosphoribosyl transferase and orotidylic acid decarboxylase activities in liver and Morris hepatomas."
3.	Carcinoma (Carcinomatosis) 11/15/1987 - "Preliminary characterization of the human placental UMP synthase showed it to be similar to UMP synthase from the Ehrlich ascites carcinoma in subunit molecular weight, native molecular weight, isozyme pattern (although not absolute pI values), pH optima of enzymatic activities, and kinetic constants for orotidine 5'-monophosphate (Km) and 6-azauridine 5'-monophosphate (Ki) at the decarboxylase site."
4.	Candidiasis (Moniliasis) 10/01/2003 - "We showed that URA3 position affected orotidine 5'-monophosphate decarboxylase activity, hyphal morphogenesis, adherence, and mortality in murine disseminated candidiasis. "
5.	Ascites 11/15/1987 - "Preliminary characterization of the human placental UMP synthase showed it to be similar to UMP synthase from the Ehrlich ascites carcinoma in subunit molecular weight, native molecular weight, isozyme pattern (although not absolute pI values), pH optima of enzymatic activities, and kinetic constants for orotidine 5'-monophosphate (Km) and 6-azauridine 5'-monophosphate (Ki) at the decarboxylase site."

Related Drugs and Biologics

1.	Carboxy-Lyases
2.	Orotate Phosphoribosyltransferase
3.	Enzymes
4.	Dihydroorotate Dehydrogenase
5.	Orotidine-5'-Phosphate Decarboxylase (Orotidine 5 Phosphate Decarboxylase)
6.	Uridine Monophosphate (UMP)
7.	Transferases
8.	Proteins (Proteins, Gene)
9.	Isoenzymes
10.	Azauridine (6 Azauridine)