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norfenefrine

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RN given refers to cpd without isomeric designation; structure

Also Known As:

3-octopamine; A.S. COR; Gödecke Brand of Norfenefrine Hydrochloride; Norfenefrin Ziethen; Norfenefrin-ratiopharm; Novadral; SmithKline Beecham Brand of Norfenefrine Hydrochloride; Ziethen Brand of Norfenefrine Hydrochloride; alpha-(aminomethyl)-3-hydroxybenzyl alcohol; m-octopamine; norfenefrine citrate (1:1), (R)-(R-(R*,R*))-isomer; norfenefrine citrate (1:1), (R-(R*,R*))-isomer; norfenefrine hydrochloride; norfenefrine hydrochloride, (+,-)-isomer; norfenefrine hydrochloride, (R)-isomer; norfenefrine hydrochloride, (S)-isomer; norfenefrine sulfate; norfenefrine, (+)-isomer; norfenefrine, (+,-)-isomer; norfenefrine, (-)-isomer; norfenefrine, 2H-labeled cpd; norphenylephrine; ratiopharm Brand of Norfenefrine Hydrochloride

Networked: 22 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hinder, Frank: 3 articles (01/2005 - 03/2003)
2.	Baba, Hideo A: 3 articles (01/2005 - 03/2003)
3.	Stubbe, Henning D: 3 articles (01/2005 - 03/2003)
4.	Wohlschlaeger, Jeremias: 2 articles (01/2005 - 07/2004)
5.	Schmitz, Klaus J: 2 articles (01/2005 - 07/2004)
6.	August, Christian: 2 articles (07/2004 - 03/2003)
7.	Takeda, Nobuakira: 1 article (01/2005)
8.	Kawaguchi, Naomasa: 1 article (01/2005)
9.	Takeda, Atsushi: 1 article (01/2005)
10.	Grabellus, Florian: 1 article (07/2004)

Related Diseases

1.	Hypotension (Low Blood Pressure) 01/01/1992 - "In a first study 10 pregnant women with hypotension and severe orthostatic dysregulation were treated with norfenefrine hydrochloride (3 x 45 mg p. " 01/01/1992 - "[Therapy of hypotension in pregnancy using norfenefrine hydrochloride with special reference to the effects on fetal circulation--initial observations]." 06/25/1966 - "[On the ambulant treatment of hypotension and hypotensive disorders of the circulation with Novadral]." 08/11/1983 - "[Hypotension therapy with norfenefrine--oral administration also dependably effective]."
2.	Necrosis 11/01/1958 - "[Study on the necrosis-inducing properties of noradrenal and novadral injected intradermally]." 03/01/2003 - "Norfenefrine-masked hypovolemia caused disseminated cardiac cell necrosis independent of endotoxemia (p < .05 vs. ENDO). "
3.	Shock 07/01/2004 - "HSP 72 was elevated in animals with norfenefrine-refractory shock compared to survivors ( p=0.015). " 05/28/1960 - "[Clinical experiences with the treatment of states of circulatory collapse with novadral]." 09/01/1956 - "[Contribution to the management of acute circulatory failure in internal medicine with novadral]." 04/01/1960 - "[Depot novadral as a prophylactic in circulatory collapse after epidural anesthesia]." 03/01/2003 - "Endotoxemia induced norfenefrine-refractory shock (p < .05 vs. the other groups) and contributed to renal dysfunction only during vasoconstrictor-masked hypovolemia. "
4.	Hypovolemia 07/01/2004 - "Eighteen adult-instrumented sheep and three healthy controls were randomly assigned to one of three groups: (a) norfenefrine-masked hypovolemia plus endotoxemia (NMH+ENDO); (b) norfenefrine-masked hypovolemia without endotoxemia (NMH); (c) recurrent endotoxemia during normovolemia (ENDO); and (d) normovolemia without endotoxemia (CONTROLS). " 03/01/2003 - "Hypovolemia was induced by hemorrhage (about 23 mL x kg(-1)) until mean arterial pressures reached 40 mm Hg. Endotoxin (0.5 microg x k(-1)) was then injected after 4, 16, 28, and 40 hrs. The NMH group received norfenefrine-masked hypovolemia but no endotoxin. " 03/01/2003 - "In the norfenefrine-masked hypovolemia plus endotoxemia (NMH+ENDO) group, mean arterial pressures of 80 mm Hg were maintained by using the alpha1-adrenergic catecholamine norfenefrine for 52 hrs during hypovolemia. " 03/01/2003 - "Norfenefrine-masked hypovolemia caused disseminated cardiac cell necrosis independent of endotoxemia (p < .05 vs. ENDO). " 03/01/2003 - "Endotoxemia induced norfenefrine-refractory shock (p < .05 vs. the other groups) and contributed to renal dysfunction only during vasoconstrictor-masked hypovolemia. "
5.	Endotoxemia 07/01/2004 - "Eighteen adult-instrumented sheep and three healthy controls were randomly assigned to one of three groups: (a) norfenefrine-masked hypovolemia plus endotoxemia (NMH+ENDO); (b) norfenefrine-masked hypovolemia without endotoxemia (NMH); (c) recurrent endotoxemia during normovolemia (ENDO); and (d) normovolemia without endotoxemia (CONTROLS). " 03/01/2003 - "In the norfenefrine-masked hypovolemia plus endotoxemia (NMH+ENDO) group, mean arterial pressures of 80 mm Hg were maintained by using the alpha1-adrenergic catecholamine norfenefrine for 52 hrs during hypovolemia. " 03/01/2003 - "Norfenefrine-masked hypovolemia caused disseminated cardiac cell necrosis independent of endotoxemia (p < .05 vs. ENDO). " 03/01/2003 - "Endotoxemia induced norfenefrine-refractory shock (p < .05 vs. the other groups) and contributed to renal dysfunction only during vasoconstrictor-masked hypovolemia. " 01/01/2005 - "Experimental groups included (1) norfenefrine-masked hypovolemia plus endotoxemia (NMH+ENDO) (n=6), (2) norfenefrine-masked hypovolemia without endotoxemia (NMH) (n=6), (3) recurrent endotoxemia during normovolemia (ENDO) (n=6), and (4) healthy untreated controls (CON) (n=3). "

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Related Therapies and Procedures

1.	Catheters
2.	Epidural Anesthesia
3.	Oral Administration