naringin

08/05/2014 - "Further results suggest that angiogenesis was improved via naringin-mediated inhibition of hyperglycemia, oxidative stress, down-regulation of inflammatory mediator expression and up-regulation of growth factor expression, leading to improved wound healing of DFU."
01/01/2011 - "Thus, naringin might be a good candidate to reduce genotoxic risk associated with hyperglycemia and may provide decreases in the development of secondary malignancy and abnormal reproductive outcomes risks, which seems especially important for diabetic patients."
02/01/2012 - "Naringin ameliorates atherogenic dyslipidemia but not hyperglycemia in rats with type 1 diabetes."
01/01/2011 - "In conclusion, naringin confers an appealing protective effect against diabetes-induced chromosomal instability towards rat somatic and germinal cells which might be explained partially via diminishing the de novo free radical generation induced by hyperglycemia. "
11/01/2012 - "The present study was hypothesized to investigate the beneficial effects of hesperidin and naringin on hyperglycemia-induced oxidative damage in HFD/STZ-induced diabetic rats. "

07/01/2015 - "Our findings provide a molecular basis by which naringin restores the TNF-α-induced damage in MSCs and provide novel insights into the application of naringin in the MSC-based treatments for inflammation-induced bone injury."
07/01/2015 - "Yet the impact of naringin on inflammation-affected bone marrow-derived mesenchymal stem cell (BM-MSC), a promising tool for the regenerative treatment of bone injury, remained to be investigated. "
04/01/2015 - "Naringin inhibits gamma radiation-induced oxidative DNA damage and inflammation, by modulating p53 and NF-κB signaling pathways in murine splenocytes."
02/01/2015 - "[Research progress on Drynaria fortunei naringin on inflammation and bone activity]."
05/15/2014 - "These findings suggest that naringin treatment attenuates renal dysfunction and structural damage through the reduction of oxidative stress, mitochondrial dysfunction, inflammation and apoptosis in the kidney. "

05/01/2013 - "The study suggests that naringin administration may represent an effective treatment for osteoporosis."
02/01/2015 - "In animal experimental, naringin was useful for osteoporosis, and the mechanisms are in-depth studies. "
01/01/2015 - "This study was designed to investigate the impact of combined treatment with naringin and treadmill exercise on osteoporosis in ovariectomized (OVX) rats. "
01/01/2015 - "Previous studies have demonstrated the effect of naringin (NG) or treadmill exercise (EX) on osteoporosis, however, reports about effects of NG plus EX on osteoporosis are limited. "
09/26/2014 - "The present study is an effort to explore the anti-osteoporosis potential of naringin in vivo and in vitro. "

09/01/2004 - "From this study, it may be concluded that all doses of naringin provided a significant amelioration of hypoglycaemic and antioxidant activity in STZ-induced diabetic rats, however, the greatest effect of naringin was observed at 80 mg/kg body weight."
01/01/2015 - "No significant differences were observed among groups in final body weight, carcass weight and internal organs weights (P>0.05) apart from liver that decreased linearly with increased levels of naringin (P-linear<0.05). "
04/01/2014 - "Although consecutive and/or isolated periods of significant body weights and food consumption decreases were relevant to naringin administration, they were not considered toxicologically significant. "
12/27/2012 - "Rats were injected with 3-NP (10mg/kg body weight/day, i.p.) for 2 weeks to develop neurodegeneration, while naringin (80 mg/kg body weight/day, orally) was administered throughout the experimental period, 1h prior to 3-NP exposure. "
10/01/2012 - "The results revealed that naringin supplementation at 20, 40, and 80 mg/kg significantly increased body weight of CS-induced rats as compared to that in the CS group. "

08/15/2009 - "Seven days naringin (50 and 100 mg/kg) treatment significantly improved neurobehavioral alterations (improved locomotor activity, inclined beam walking and reduced resistance to lateral push, transfer latency) as compared to control ischemia reperfusion. "
08/15/2009 - "Present study suggests the protective effect of naringin and its therapeutic potential against ischemia reperfusion induced and related behavioral alterations in rats."
08/15/2009 - "The present study was conducted with an aim to explore the possible role of naringin against ischemia reperfusion induced-neurobehavioral alterations, oxidative damage, cellular and histopathological alterations in cortex, striatum, hippocampus areas of brain. "
07/01/2014 - "Naringin is neuroprotective in ischemia and other disease models. "
06/19/2010 - "Naringin (50 and 100 mg/kg) treatment significantly attenuated neurobehavioral alterations, oxidative damage and restored mitochondrial enzyme complex activities as compared to control (ischemia reperfusion) group. "