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naftazone

RN given refers to 1,2-naphthoquinone monosemicarbazone cpd

Also Known As:

1,2-naphthoquinone-2-semicarbazone; Etioven; Haemostop; Mediaven; Metorene

Networked: 8 relevant articles (4 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        naftazone: 8
- Quinones: 434
  - Naphthoquinones: 418
    - naftazone: 8
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - naftazone: 8

Experts

1.	Corvol, Jean-Christophe: 2 articles (01/2019 - 08/2012)
2.	Galitzky, Monique: 2 articles (01/2019 - 08/2012)
3.	Lacomblez, Lucette: 2 articles (01/2019 - 08/2012)
4.	Rascol, Olivier: 2 articles (01/2019 - 08/2012)
5.	Azulay, Jean-Philippe: 1 article (01/2019)
6.	Benel, Laurent: 1 article (01/2019)
7.	Boraud, Thomas: 1 article (01/2019)
8.	Chaigneau, Véronique: 1 article (01/2019)
9.	Cormier-Dequaire, Florence: 1 article (01/2019)
10.	Debilly, Bérengère: 1 article (01/2019)

Related Diseases

1.	Dyskinesias (Dyskinesia) 01/01/2019 - "This study did not confirm previous results on the efficacy of naftazone on dyskinesia nor motor fluctuations highlighting the problem of translating results obtained in preclinical models into clinical trials. " 01/01/2019 - "We conducted a double-blind randomized placebo-controlled cross-over trial in PD patients with motor fluctuations and dyskinesia testing naftazone 160 mg/day versus placebo for 14 days. " 08/01/2012 - "On diaries, 5/7 patients responded to naftazone for 'ON-time with troublesome dyskinesia' (reduced time, treatment effect: -49 [95% CI: -93/-4] min, P = 0.03), 6/7 regarding 'ON-time without troublesome dyskinesia' (increased time, treatment effect: 35 [-19/88], P = 0.2). "
2.	Parkinson Disease (Parkinson's Disease) 08/01/2012 - "To explore for the first time the tolerability and efficacy of naftazone in patients with Parkinson's disease (PD). " 08/01/2012 - "A proof-of-concept, randomized, placebo-controlled, multiple cross-overs (n-of-1) study of naftazone in Parkinson's disease." 01/01/2019 - "Naftazone in advanced Parkinson's disease: An acute L-DOPA challenge randomized controlled trial."
3.	Metrorrhagia (Spotting) 01/01/1984 - "They show a great improvement with the periods becoming normal and metrorrhagia disappearing in 12 out of 13 cases where naftazone was used and in only 1 out of 12 cases where the placebo was used."
4.	Pathologic Constriction (Stenosis) 02/26/1998 - "Oral administration of naftazone significantly decreased portal pressure in rats with portal vein stenosis; this decrease depended on a significant reduction of portal blood flow. "
5.	Portal Hypertension 02/26/1998 - "The aim of this study was to evaluate the haemodynamic effects of acute and chronic administration of naftazone in rats with portal hypertension. "

Related Drugs and Biologics

1.	naftazone
2.	Ketorolac
3.	Mefenamic Acid (Pontal)
4.	Levodopa (L Dopa)
5.	Cytotoxins (Cytolysins)
6.	1,2-naphthoquinone

Related Therapies and Procedures

1.	Oral Administration
2.	Epidural Analgesia
3.	Therapeutics