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pyranine

structure

Also Known As:

1-hydroxypyrene-3,6,8-trisulfonic acid; 8-hydroxypyrene-1,3,6-trisulfonate; 8-hydroxypyrene-1,3,6-trisulfonic acid; D.C. Green No. 8; 8-hydroxy-1,3,6-pyrenetrisulfonic acid trisodium salt

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Sulfur Compounds: 135
  - Sulfur Acids
    - Sulfonic Acids: 3
      - Arylsulfonic Acids
        Arylsulfonates: 1
        pyranine: 5

Experts

1.	Morilla, Maria Jose: 2 articles (05/2011 - 01/2009)
2.	Romero, Eder L: 2 articles (05/2011 - 01/2009)
3.	Qian, Steven Y: 1 article (08/2011)
4.	Gu, Yan: 1 article (08/2011)
5.	Mallik, Sanku: 1 article (08/2011)
6.	Friesner, Daniel L: 1 article (08/2011)
7.	Nyren-Erickson, Erin K: 1 article (08/2011)
8.	Haldar, Manas K: 1 article (08/2011)
9.	Cabrera, Mirel: 1 article (05/2011)
10.	Higa, Leticia: 1 article (05/2011)

Related Diseases

1.	AIDS-Related Complex (ARC) 01/01/2009 - "ARC inner aqueous content remained inside the phago-lysosomal system of J-774 cells beyond the first incubation hour at 37 degrees C, as revealed by pyranine loaded in ARC. " 05/01/2011 - "The fluorescence of M-like cells upon 1 and 2h incubation with ARC loaded with the hydrophobic dye Rhodamine-PE (Rh-PE) and the hydrophilic dye pyranine (HPTS) dissolved in the aqueous space, was 4 folds higher than upon incubation with equally labeled liposomes. "
2.	Neoplasms (Cancer) 05/14/2001 - "Release of both a highly-water soluble fluorescent contents marker, pyranine, and an amphipathic cytotoxic anti-cancer drug, doxorubicin, from copolymer-modified liposomes was shown to be dependent on pH, the concentration of copolymer, the presence of other polymers such as polyethylene glycol, and the method of preparation. "
3.	Dehydration (Water Stress) 10/01/1997 - "The dehydration reaction of bicarbonate was measured using the fluorescent pH indicator, 8-hydroxypyrene-1,3,6-trisulfonate (pyranine), in combination with stopped-flow spectrofluorometry. "
4.	Alzheimer Disease (Alzheimer's Disease) 08/01/2011 - "In addition, we also demonstrate that the liposomes incorporating the pyranine lipid are able to distinguish between dilute serum from healthy individuals and serum containing elevated chondroitin sulfate (simulated serum from an Alzheimer's disease patient)."

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	pyranine
3.	Rhodamines
4.	Polymers
5.	Polyethylene Glycols (Polyethylene Glycol)
6.	Doxorubicin (Adriamycin)
7.	Chondroitin Sulfates (Chondroitin Sulfate)