cyclothiazide

01/01/1985 - "Comparison of cyclothiazide and hydrochlorthiazide in hypertension. "
08/26/1977 - "Three dosage combinations of clonidine and cyclothiazide were tested in at least 20 patients each, under clinical (4 weeks) and oupatients (longterm) conditions, in order to find a suitable combination with fewer side effects than the single drugs with at least equal efficacy for the longterm treatment of hypertension. "
02/28/1981 - "[Short-term clinical trial of a clonidine-cyclothiazide combination in the treatment of arterial hypertension]."
10/16/1969 - "[Treatment of hypertension with cyclothiazide (Doburil) and chlorthalidone (Hygroton)]."
11/30/1983 - "[Clonidine-cyclothiazide combination in the therapy of arterial hypertension. "

05/01/2004 - "The novel finding of this study is that carrageenan-induced inflammation, in the presence of cyclothiazide, an inhibitor of AMPA receptor desensitization, produces a sustained facilitation of the AMPA-mediated membrane current and rises in [Ca2+]i in both the soma and proximal dendrites of SG neurons recorded on the injected side 3 h after the induction of inflammation. "

09/01/1999 - "To measure the output of transient amacrine cells, we recorded glycinergic inhibitory postsynaptic currents (IPSCs) from ganglion cells, and found that these were also enhanced by cyclothiazide. "
09/01/1995 - "Cyclothiazide also enhanced the amplitude and duration of both the ON and OFF light-evoked (L-) EPSCs recorded in ON-OFF ganglion cells. "
09/01/1995 - "Cyclothiazide selectively enhanced the AMPA/KA receptor-mediated component of ganglion cells EPSCs, suggesting that desensitization of AMPA/KA receptors shape transient L-EPSCs."
09/01/2001 - "Both cyclothiazide (10 microM-100 microM) and the novel drug 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluoro-phenoxyacetamide (PEPA, 20 microM-100 microM), which selectively enhance responses mediated by AMPA-preferring receptors, enhanced glutamate-induced responses of ganglion cells. "
09/01/1999 - "Current responses elicited by puffing glycine onto ganglion cell dendrites were not affected by cyclothiazide, indicating that the enhancement of glycinergic IPSCs was not due to a direct effect on glycine receptors. "

01/01/2005 - "Cyclothiazide alone did not evoke seizures. "
01/01/2005 - "NMDA-insensitive self-sustaining seizures were also evoked by the combination of AMPA and cyclothiazide. "
08/01/2000 - "The significant induction of c-fos mRNA by audiogenic seizures in PTU rats or by AMPA- or cyclothiazide-induced seizures in naive rats was prominent in the IC. "
01/01/2005 - "In particular, coadministration of bicuculline (118 pmol) with either carbachol (328 pmol) or cyclothiazide (1.2 nmol) triggered continuous self-sustaining seizures (status epilepticus; SE). "
08/01/2000 - "NBQX suppressed the expression of c-fos mRNA in the IC induced by AMPA-induced seizures but did not suppress c-fos mRNA in PTU rats or rats with cyclothiazide-induced seizures. "

02/01/1979 - "Cyclothiazide and atenolol once daily in essential hypertension."
02/04/1978 - "The long terme hemodynamic effect of cyclothiazide 3 mg-triamterene 150 mg was studied in 10 patients with permanent essential hypertension. "