panaxatriol

a protopanaxatriol with the side chain cyclized into a pyran which is an artifact of acidic hydrolysis

Also Known As:

panaxatriol, (3beta,6alpha,12beta)-isomer; (3 beta,6 alpha,12 beta,20R)-20,25-epoxydammarane- 3,6,12-triol

Networked: 21 relevant articles (4 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Ginsenosides: 1010
        panaxatriol: 21
Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - Ginsenosides: 1010
      - panaxatriol: 21

Experts

1.	Huang, Yongliang: 2 articles (06/2016 - 01/2014)
2.	Qi, Hongyi: 2 articles (06/2016 - 01/2014)
3.	Wan, Fang: 2 articles (06/2016 - 01/2014)
4.	Wang, Li: 2 articles (06/2016 - 01/2014)
5.	Wu, Chunjie: 2 articles (06/2016 - 01/2014)
6.	Yang, Huarong: 2 articles (06/2016 - 01/2014)
7.	Zhang, Wenwu: 2 articles (06/2016 - 01/2014)
8.	Gao, Yongxiang: 1 article (01/2022)
9.	Gong, Yuanyuan: 1 article (01/2022)
10.	He, Qingman: 1 article (01/2022)

Related Diseases

1.	Fibrosis (Cirrhosis) 06/01/2023 - "Corrigendum to "Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation" [Free Radic. " 01/01/2022 - "Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation." 01/01/2022 - "We investigated the role of oxidative stress in myocardial fibrosis and the protective effect of panaxatriol saponin (PTS) against myocardial infarction (MI)-induced cardiac fibrosis and explored the underlying mechanisms. " 11/01/2008 - "Influence of ginsenoside Rg1, a panaxatriol saponin from Panax notoginseng, on renal fibrosis in rats with unilateral ureteral obstruction."
2.	Myocardial Infarction 06/01/2023 - "Corrigendum to "Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation" [Free Radic. " 01/01/2022 - "Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation." 01/01/2022 - "We investigated the role of oxidative stress in myocardial fibrosis and the protective effect of panaxatriol saponin (PTS) against myocardial infarction (MI)-induced cardiac fibrosis and explored the underlying mechanisms. "
3.	Brain Ischemia (Cerebral Ischemia) 05/01/2002 - "To study the protective effects and its mechanism of Panaxatriol Saponins isolated from Panax notoginseng (PTS) on focal cerebral ischemia in rat brain. " 05/01/2002 - "[Protective effects and its mechanism of panaxatriol saponins isolated from Panax notoginseng on cerebral ischemia]."
4.	Contracture 06/01/2010 - "Total saponin and panaxatriol significantly improved I/R-induced myocardial dysfunction by increasing left ventricular development pressure, (-dP/dt)/(+dP/dt) and time to contracture. "
5.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2020 - "To develop more potent therapeutic agents against myocardial ischemia/reperfusion (MI/R) injury from natural products, a novel series of heterocycle ring-fused panaxatriol derivatives were designed and synthesized. " 01/01/2020 - "Synthesis and biological evaluation of panaxatriol derivatives against myocardial ischemia/reperfusion injury in the rat." 01/01/2022 - "Pretreatment with Panaxatriol Saponin Attenuates Mitochondrial Apoptosis and Oxidative Stress to Facilitate Treatment of Myocardial Ischemia-Reperfusion Injury via the Regulation of Keap1/Nrf2 Activity." 06/01/2010 - "The aim of the present study was to evaluate the protective effect of ginseng total saponin, panaxadiol and panaxatriol, which are the major components of Panax ginseng, against myocardial ischemia/reperfusion (I/R) injury in isolated rat hearts. "

Related Drugs and Biologics

1.	Saponins
2.	panaxadiol
3.	Ginsenosides
4.	Matrix Metalloproteinase 9 (Gelatinase B)
5.	Sterols
6.	Proteins (Proteins, Gene)
7.	Oxygen (Dioxygen)
8.	Lipids
9.	Glycosides
10.	Glucose (Dextrose)