blasticidin S

RN given refers to (S)-isomer; structure

Also Known As:

blasticidin S, carbamodithioate, (S)-isomer; blasticidin S, dodecyl sulfate, (S)-isomer; blasticidin S, hydrochloride, (S)-isomer; blasticidin S, methyl sulfate, (S)-isomer; blasticidin S, monohydrochloride, (S)-isomer; 1-(1'-cytosinyl)-4-(L-3'-amino-5'-(1''-N-methylguanidino)valerylamino)-1,2,3,4-tetradeoxy-beta-D-erythro-hex-2-enuronic acid

Networked: 13 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chen, Ridao: 1 article (01/2022)
2.	Feng, Jianqiang: 1 article (01/2022)
3.	Gao, Jin-Ming: 1 article (01/2022)
4.	Hou, Xueli: 1 article (01/2022)
5.	Lee, Yu-Hsuan: 1 article (01/2022)
6.	Liu, Hung-Wen: 1 article (01/2022)
7.	Liu, Xiao: 1 article (01/2022)
8.	Ruszczycky, Mark W: 1 article (01/2022)
9.	Wang, Binju: 1 article (01/2022)
10.	Zhou, Jiahai: 1 article (01/2022)

Related Diseases

1.	T-Cell Leukemia (Leukemia, T Cell) 10/01/2008 - "To analyse the protective effects of long-term expression of the CCR5Delta32 protein, recombinant lentiviral vectors were used to deliver the CCR5Delta32 gene into human cell lines and primary peripheral blood mononuclear cells that had been immortalized by human T-cell leukemia virus type 1. Blasticidin S-resistant cell lines expressing the lentivirus-encoded CCR5Delta32 showed a significant reduction in HIV-1 Env-mediated fusion assays. "
2.	Hamman-Rich Syndrome (Hamman Rich Syndrome) 04/01/1994 - "Blasticidin S should be kept in mind as a causative agent of acute interstitial pneumonia." 04/01/1994 - "[A case of acute interstitial pneumonia caused by blasticidin S]." 04/01/1994 - "A 41-year-old male developed acute interstitial pneumonia after inhalation of Blasticidin S, an antibiotic effective against rice blast disease. "
3.	Starvation 01/01/2017 - "Our study demonstrates that chloramphenicol and blasticidin S that target the peptidyl transferase centre of the bacterial ribosome can then inhibit dissociation of 70S ribosome mediated by (i) unfolded protein, (ii) translation factors or (iii) low Mg+2 concentrations in vitro and thereby suppresses ribosomal degradation during carbon starvation in vivo. "
4.	Pneumonia (Pneumonitis) 02/01/1969 - "Light and electron microscope studies on experimental pneumonitis induced by blasticidin-S, with special reference to alveolar regeneration."
5.	Poisoning 04/01/1996 - "Poisoning following blasticidin S ingestion remains a challenge to acute health care physicians. " 04/01/1996 - "A total of 28 blasticidin S poisoning exposures, including 24 suicidal ingestions, were recorded. " 04/01/1996 - "In an attempt to delineate the clinical pictures of blasticidin S poisoning, a retrospective study covering an 8.5-y period was then conducted. " 04/01/1996 - "Clinical experience in poisonings following exposure to blasticidin S, a curiously strong fungicide." 02/01/1987 - "We presented the first 4 reported cases of acute poisoning from ingesting blasticidin S for suicidal attempts. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Recombinant Proteins
3.	Proteins (Proteins, Gene)
4.	Peptidyl Transferases (Peptidyltransferase)
5.	Chloramphenicol (Chloromycetin)
6.	Carbon
7.	Aclarubicin
8.	RNA (Ribonucleic Acid)
9.	Ricin
10.	Phleomycins